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• W2518567858 endingPage "e0161608" @default.
• W2518567858 startingPage "e0161608" @default.
• W2518567858 abstract "Live birth has emerged as a reproductive strategy many times across vertebrate evolution; however, mammals account for the majority of viviparous vertebrates. Marsupials are a mammalian lineage that last shared a common ancestor with eutherians (placental mammals) over 148 million years ago. Marsupials are noted for giving birth to highly altricial young after a short gestation, and represent humans' most distant viviparous mammalian relatives. Here we ask what insight can be gained into the evolution of viviparity in mammals specifically and vertebrates in general by analyzing the global uterine transcriptome in a marsupial. Transcriptome analyses were performed using NextGen sequencing of uterine RNA samples from the gray short-tailed opossum, Monodelphis domestica. Samples were collected from late stage pregnant, virgin, and non-pregnant experienced breeders. Three different algorithms were used to determine differential expression, and results were confirmed by quantitative PCR. Over 900 opossum gene transcripts were found to be significantly more abundant in the pregnant uterus than non-pregnant, and over 1400 less so. Most with increased abundance were genes related to metabolism, immune systems processes, and transport. This is the first study to characterize the transcriptomic differences between pregnant, non-pregnant breeders, and virgin marsupial uteruses and helps to establish a set of pregnancy-associated genes in the opossum. These observations allowed for comparative analyses of the differentially transcribed genes with other mammalian and non-mammalian viviparous species, revealing similarities in pregnancy related gene expression over 300 million years of amniote evolution." @default.
• W2518567858 created "2016-09-16" @default.
• W2518567858 creator A5009031897 @default.
• W2518567858 creator A5034790959 @default.
• W2518567858 creator A5055102276 @default.
• W2518567858 date "2016-09-06" @default.
• W2518567858 modified "2023-10-11" @default.
• W2518567858 title "Transcriptomic Changes Associated with Pregnancy in a Marsupial, the Gray Short-Tailed Opossum Monodelphis domestica" @default.
• W2518567858 cites W1577577364 @default.
• W2518567858 cites W1594381616 @default.
• W2518567858 cites W1754782457 @default.
• W2518567858 cites W1920919905 @default.
• W2518567858 cites W1965536495 @default.
• W2518567858 cites W1968079920 @default.
• W2518567858 cites W1969975551 @default.
• W2518567858 cites W1970383372 @default.
• W2518567858 cites W1976166485 @default.
• W2518567858 cites W1976622662 @default.
• W2518567858 cites W1981287782 @default.
• W2518567858 cites W1985640811 @default.
• W2518567858 cites W1988023818 @default.
• W2518567858 cites W1990197447 @default.
• W2518567858 cites W1998973138 @default.
• W2518567858 cites W2000386160 @default.
• W2518567858 cites W2000525981 @default.
• W2518567858 cites W2006852393 @default.
• W2518567858 cites W2012099404 @default.
• W2518567858 cites W2015206641 @default.
• W2518567858 cites W2016511759 @default.
• W2518567858 cites W2021403140 @default.
• W2518567858 cites W2022472106 @default.
• W2518567858 cites W2022783679 @default.
• W2518567858 cites W2036507321 @default.
• W2518567858 cites W2048062460 @default.
• W2518567858 cites W2050183512 @default.
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• W2518567858 cites W2057158848 @default.
• W2518567858 cites W2062026173 @default.
• W2518567858 cites W2067700651 @default.
• W2518567858 cites W2079672500 @default.
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• W2518567858 cites W2084421005 @default.
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• W2518567858 cites W2088777023 @default.
• W2518567858 cites W2090427940 @default.
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• W2518567858 cites W2101671848 @default.
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• W2518567858 cites W2155482108 @default.
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• W2518567858 doi "https://doi.org/10.1371/journal.pone.0161608" @default.
• W2518567858 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5012577" @default.
• W2518567858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27598793" @default.
• W2518567858 hasPublicationYear "2016" @default.
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