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- W2519031222 abstract "Objectives: The aim of this study was to investigate the safety and efficacy of propofol sedation with a target-controlled infusion (TCI) computer-assisted pump and bispectral index (BIS) monitoring in elderly patients during endoscopic retrograde cholangiopancreateography (ERCP). Methods: Included were 150 consecutive EPCP proc edures elderly patients under propofol sedation with a TCI system. Patients were divided into 3 groups: group A, age 50-70 years (n=50); group B, age71-80 years (n=50); group C, age >80 years (n=50). We compared the propofol dose and adverse events (hypotension and hypoxemia) during ERCP. Results: Older patients required a l ower target concentration of propofol with higher age period: Median target concentration are respectively 2.6μg/mL,2.1μg/mL and 1.6μg/mL in the three groups. Hypotension tended to occur in the younger group, and hypoxemia occurred at a significantly higher rate in the older groups, although the number of cases was small. Low preoperative systolic blood pressure (<80 mm Hg) was associated with hy potension and abnormal pulmonary function was associated with hypoxemia in groups B and C. Conclusions: Elderly patients required lower doses of propofol with TCI/BIS system than younger patients. Attention to hypoxemia is necessary in elderly patients, particularly patients with abnormal pulmonary function." @default.
- W2519031222 created "2016-09-23" @default.
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- W2519031222 date "2016-01-01" @default.
- W2519031222 modified "2023-09-24" @default.
- W2519031222 title "Target Control Infusion (TCI) Computer-Assisted Pump and Bispectral Index (BIS ) Monitoring Sedation System in Elderly Patients during Endoscopic Retrograde Cholangiopancreateography (ERCP)" @default.
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- W2519031222 doi "https://doi.org/10.2991/bbe-16.2016.77" @default.
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