FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2519345496> ?p ?o ?g. }

• W2519345496 endingPage "496" @default.
• W2519345496 startingPage "490" @default.
• W2519345496 abstract "To prevent transmission of zoonotic microorganisms from pig transplants to human recipients when performing xenotransplantation using pig cells, tissues, or organs, donor pigs have to be carefully characterized. Göttingen minipigs (GöMP) are often used for various biomedical investigations and are well characterized concerning the presence of numerous bacteria, fungi, viruses, and parasites. Recently, we studied the prevalence and expression of porcine endogenous retroviruses and the prevalence of hepatitis E virus (HEV) in GöMP. Here, we studied the presence of the porcine cytomegalovirus (PCMV) and porcine lymphotropic herpesviruses (PLHV) and extended testing for hepatitis E virus (HEV).PCR, nested PCR, real-time PCR, real-time RT-PCR, and Western blot analyses were used to estimate the prevalence of PCMV, PLHV-1, PLHV-2, PLHV-3, and HEV.Using different PCR methods, and different source materials, PCMV was found in 10 of 26 adult GöMP, which had been derived originally by cesarean section and kept under specified pathogen-free conditions. Only highly sensitive methods gave positive results, not methods of lower sensitivity. The virus load in all positive animals was low (<100-200 copies per mL). PLHV-1, PLHV-2, and PLHV-3 were not detected by PCR; however, an anti-PLHV immune response was found in one of 10 animals tested by Western blot analyses. HEV was detected by RT-PCR in two of nine tested animals, but no anti-HEV immune response was observed.Using highly sensitive methods, PCMV, HEV, and PLHV were found in some GöMP, suggesting that these viruses may be introduced through the placenta. The results show that highly sensitive methods are required to characterize pigs to be used for xenotransplantation to prevent virus transmission." @default.
• W2519345496 created "2016-09-23" @default.
• W2519345496 creator A5069981009 @default.
• W2519345496 creator A5070322498 @default.
• W2519345496 creator A5077728345 @default.
• W2519345496 creator A5079303125 @default.
• W2519345496 creator A5082086461 @default.
• W2519345496 date "2016-09-11" @default.
• W2519345496 modified "2023-10-01" @default.
• W2519345496 title "Extended microbiological characterization of Göttingen minipigs: porcine cytomegalovirus and other viruses" @default.
• W2519345496 cites W1536279413 @default.
• W2519345496 cites W1612769500 @default.
• W2519345496 cites W1668746819 @default.
• W2519345496 cites W1976507427 @default.
• W2519345496 cites W1992003850 @default.
• W2519345496 cites W2017876935 @default.
• W2519345496 cites W2022995241 @default.
• W2519345496 cites W2025571326 @default.
• W2519345496 cites W2031697996 @default.
• W2519345496 cites W2036688433 @default.
• W2519345496 cites W2038173080 @default.
• W2519345496 cites W2040034628 @default.
• W2519345496 cites W2045974472 @default.
• W2519345496 cites W2048794853 @default.
• W2519345496 cites W2052011721 @default.
• W2519345496 cites W2059615344 @default.
• W2519345496 cites W2068857632 @default.
• W2519345496 cites W2095813382 @default.
• W2519345496 cites W2106107950 @default.
• W2519345496 cites W2125570295 @default.
• W2519345496 cites W2132660121 @default.
• W2519345496 cites W2134866413 @default.
• W2519345496 cites W2236572271 @default.
• W2519345496 cites W2265369535 @default.
• W2519345496 cites W2312631434 @default.
• W2519345496 cites W2316023780 @default.
• W2519345496 cites W2333531741 @default.
• W2519345496 cites W81136551 @default.
• W2519345496 doi "https://doi.org/10.1111/xen.12265" @default.
• W2519345496 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27615035" @default.
• W2519345496 hasPublicationYear "2016" @default.
• W2519345496 type Work @default.
• W2519345496 sameAs 2519345496 @default.
• W2519345496 citedByCount "35" @default.
• W2519345496 countsByYear W25193454962017 @default.
• W2519345496 countsByYear W25193454962018 @default.
• W2519345496 countsByYear W25193454962019 @default.
• W2519345496 countsByYear W25193454962020 @default.
• W2519345496 countsByYear W25193454962021 @default.
• W2519345496 countsByYear W25193454962022 @default.
• W2519345496 countsByYear W25193454962023 @default.
• W2519345496 crossrefType "journal-article" @default.
• W2519345496 hasAuthorship W2519345496A5069981009 @default.
• W2519345496 hasAuthorship W2519345496A5070322498 @default.
• W2519345496 hasAuthorship W2519345496A5077728345 @default.
• W2519345496 hasAuthorship W2519345496A5079303125 @default.
• W2519345496 hasAuthorship W2519345496A5082086461 @default.
• W2519345496 hasConcept C104317684 @default.
• W2519345496 hasConcept C135763542 @default.
• W2519345496 hasConcept C141071460 @default.
• W2519345496 hasConcept C159047783 @default.
• W2519345496 hasConcept C203014093 @default.
• W2519345496 hasConcept C2522874641 @default.
• W2519345496 hasConcept C2776409557 @default.
• W2519345496 hasConcept C2776460866 @default.
• W2519345496 hasConcept C2777732132 @default.
• W2519345496 hasConcept C2778442404 @default.
• W2519345496 hasConcept C2779600528 @default.
• W2519345496 hasConcept C2779820661 @default.
• W2519345496 hasConcept C2780727368 @default.
• W2519345496 hasConcept C2780777367 @default.
• W2519345496 hasConcept C2911091166 @default.
• W2519345496 hasConcept C48023723 @default.
• W2519345496 hasConcept C55493867 @default.
• W2519345496 hasConcept C71924100 @default.
• W2519345496 hasConcept C86803240 @default.
• W2519345496 hasConcept C8891405 @default.
• W2519345496 hasConcept C89423630 @default.
• W2519345496 hasConceptScore W2519345496C104317684 @default.
• W2519345496 hasConceptScore W2519345496C135763542 @default.
• W2519345496 hasConceptScore W2519345496C141071460 @default.
• W2519345496 hasConceptScore W2519345496C159047783 @default.
• W2519345496 hasConceptScore W2519345496C203014093 @default.
• W2519345496 hasConceptScore W2519345496C2522874641 @default.
• W2519345496 hasConceptScore W2519345496C2776409557 @default.
• W2519345496 hasConceptScore W2519345496C2776460866 @default.
• W2519345496 hasConceptScore W2519345496C2777732132 @default.
• W2519345496 hasConceptScore W2519345496C2778442404 @default.
• W2519345496 hasConceptScore W2519345496C2779600528 @default.
• W2519345496 hasConceptScore W2519345496C2779820661 @default.
• W2519345496 hasConceptScore W2519345496C2780727368 @default.
• W2519345496 hasConceptScore W2519345496C2780777367 @default.
• W2519345496 hasConceptScore W2519345496C2911091166 @default.
• W2519345496 hasConceptScore W2519345496C48023723 @default.
• W2519345496 hasConceptScore W2519345496C55493867 @default.
• W2519345496 hasConceptScore W2519345496C71924100 @default.
• W2519345496 hasConceptScore W2519345496C86803240 @default.
• W2519345496 hasConceptScore W2519345496C8891405 @default.

• next