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- W2519346046 abstract "A fully integrated graphene field-effect transistor (GFET) nanosensor utilizing a novel high-κ solid-gating geometry for a practical biosensor with enhanced sensitivity is presented. Herein, an “in plane” gate supplying electrical field through a 30 nm HfO2 dielectric layer is employed to eliminate the cumbrous external wire electrode in conventional liquid-gate GFET nanosensors that undesirably limits the device potential in on-site sensing applications. In addition to the advantage in the device integration degree, the transconductance level is found to be increased by about 50% over liquid-gate GFET devices in aqueous-media, thereby improves the sensitivity performance in sensor applications. As the first demonstration of biosensing applications, a small-molecule antibiotic, kanamycin A, is detected by means of an aptameric competitive affinity principle. It is experimentally shown that the label-free and specific quantification of kanamycin A with a concentration resolution at 11.5 × 10−9 m is achievable through a single direct observation of the 200 s fast bioassay without any further noise canceling. These results demonstrate the utility and practicability of the new devices in label-free biosensing as a novel analytical tool, and potentially hold great promise in other significant biomedical applications." @default.
- W2519346046 created "2016-09-23" @default.
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- W2519346046 date "2016-09-15" @default.
- W2519346046 modified "2023-10-18" @default.
- W2519346046 title "High‐κ Solid‐Gate Transistor Configured Graphene Biosensor with Fully Integrated Structure and Enhanced Sensitivity" @default.
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- W2519346046 doi "https://doi.org/10.1002/adfm.201602960" @default.
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