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• W2519463882 abstract "Retinal oximetry (RO) has been established as a non-invasive method to analyse oxygen saturation in retinal vessels. The aim of our study was to compare the RO parameters of healthy children to those in adults.A total of 200 eyes of 104 healthy subjects were examined: 20 eyes of children aged <10 years and 62 eyes of children aged 10-19 years were compared to the eyes of adult controls from five different age groups (20-29 years:n = 24; 30-39 years:n = 32; 40-49 years:n = 15; 50-59 years:n = 20, 60-80 years:n = 27; n indicates the number of analysed eyes). The oxygen saturation was estimated with the oxygen saturation measurement tool of the Retinal Vessel Analyser (RVA; IMEDOS Systems UG, Jena, Germany). The global oxygen saturations, within 1.0-1.5 optic disc diameters from the disc margin, in the peripapillary retinal arterioles (A-SO2 ; %) and venules (V-SO2 ; %) were estimated and their difference (A-V SO2 ; %) was calculated. In addition, we evaluated the mean diameter in all four major retinal arterioles (D-A; μm) and venules (D-V; μm). The ratio between venular and arterial vessel diameter (D-V/A; μm) was calculated thereafter. For statistical evaluation, anova-based linear mixed-effects models were calculated with spss® .Based on our results, younger children (<10 years) present a statistically significant lower A-SO2 and A-V SO2 when compared to adult subgroups. The D-A values revealed to be significantly lower in 10 + children when compared to the other groups, while the D-V values did not show significant differences.These data indicate that the retinal oxygen metabolism changes throughout lifetime. Therefore, normative data for different age groups are mandatory." @default.
• W2519463882 created "2016-09-23" @default.
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• W2519463882 date "2018-09-05" @default.
• W2519463882 modified "2023-10-14" @default.
• W2519463882 title "Normative values of retinal vessel oximetry in healthy children against adults" @default.
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• W2519463882 doi "https://doi.org/10.1111/aos.13726" @default.
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