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- W2519482111 abstract "tube and formed a mass 4 cm in diameter. The tubal muscularis was destroyed by the neoplasm. The tumor was soft and tan with extensive areas of necrosis. Metastatic deposits were also resected from the small and large bowel and had a similar appearance. The neoplasm was predominantly composed of mesenchymal cells which had oval nuclei and moderate amounts of cytoplasm with indistinct cell membranes (Fig. 1). Cells with enlarged or multiple nuclei were scattered through the tumor and mitotic activity was brisk. Foci of smooth muscle differentiation were also present. Foci of malignant glandular differentiation were found in the fallopian tube tumor and in the metastatic deposits (Fig. 2). These features are diagnostic of a homologous carcinosarcpma of Mullerian origin. She was given 10 courses of chemotherapy, beginning at a dose of cisplatin 50 mg/m*, doxorubicin 50 mg/m*, and cyclophosphamide 500 mg/m’. Subsequently, the doses were decreased because of bone marrow suppression. The total cumulative dose of the drugs was 487.5 mg/m* of cisplatin, 362.5 mg/m* of doxorubicin, and 3375 mg/m’ of cyclophosphamide. With the patient in complete clinical remission, restaging laparotomy was performed 2/17/86. All lymph nodes and peritoneal biopsies, including those from sites at which residual tumor was left at initial surgery, were negative for tumor. She remains clinically free of disease 31 months after initial surgery, and 20 months after second-look laparotomy." @default.
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- W2519482111 date "1989-01-01" @default.
- W2519482111 modified "2023-09-26" @default.
- W2519482111 title "CASE REPORT Carcinosarcoma of the Fallopian Tube" @default.
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