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- W2519615742 abstract "A model can be termed accurate when it consists of a proper model structure with high quality parameter estimates. In this paper, the model structure of the Cardinal Temperature Model with Inflection point, is assumed to be correct for the intended application. The parameter estimation problem of this nonlinear four-parameter predictive model is solved by applying optimal experiment design techniques. On the basis of these techniques, the model input, i.e., a set of temperature treatments is optimized with respect to a Fisher information matrix based criterion. The applicability of various design criteria as well as the effect of necessary input constraints is evaluated." @default.
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- W2519615742 date "2004-03-01" @default.
- W2519615742 modified "2023-09-26" @default.
- W2519615742 title "Constrained Input Optimization for Optimal Parameter Estimation of a Predictive Biokinetic Model" @default.
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- W2519615742 doi "https://doi.org/10.1016/s1474-6670(17)32560-0" @default.
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