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• W2519690005 endingPage "1989" @default.
• W2519690005 startingPage "1989" @default.
• W2519690005 abstract "We established a protocol using a well-established LED stimulator to measure temporal contrast sensitivities driven by sine-wave modulation of L- and M-cones in the perifovea using triple silent substitution. The stimulus was presented in an annular field (2&#x00B0; inner diameter, 13&#x00B0; outer diameter). We validated this technique by studying the contrast sensitivity of three color normal observers at 10 different temporal frequencies (between 1 and 28 Hz) over a large range of retinal illuminances (between 0.07 and 587 phot Td), spanning the complete mesopic range. In one subject, sensitivities to counterphase modulation of L- and M-cones and in-phase modulation of L, M, and S-cones were additionally measured, which putatively reflected the parvo- and magnocellular retinogeniculate pathways, respectively. Furthermore, we performed measurements of temporal contrast sensitivities as a function of frequency at 294 phot Td in two protanopes, in two deuteranopes, and in one subject with S-cone monochromacy. Quality of isolation was satisfactory and we were able to reproduce known physiological patterns of temporal vision, such as the typical temporal contrast sensitivity functions of the L- and M-cone, the parvo- and magnocellular retinogeniculate pathways, as well as the light adaptation curves. These results will help determine optimal stimulus conditions in future studies. Results from the dichromats and the S-cone monochromat also support the quality of isolation of our protocol and underpin its potential clinical value." @default.
• W2519690005 created "2016-09-23" @default.
• W2519690005 creator A5014017566 @default.
• W2519690005 creator A5054459303 @default.
• W2519690005 date "2016-09-15" @default.
• W2519690005 modified "2023-10-17" @default.
• W2519690005 title "Perifoveal L- and M-cone-driven temporal contrast sensitivities at different retinal illuminances" @default.
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• W2519690005 doi "https://doi.org/10.1364/josaa.33.001989" @default.
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