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- W2519697816 abstract "Pigs have great potential to provide preclinical models for human disease in translational research because of their similarities with humans. In this regard, porcine pluripotent cells, which are able to differentiate into cells of all three primary germ layers, might be a suitable animal model for further development of regenerative medicine. Here, we describe the current state of knowledge on apoptosis in pluripotent cells including inner cell mass (ICM), epiblast, embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). Information is focused on the apoptotic phenomenon in pluripotency, maintenance, and differentiation of pluripotent stem cells and reprogramming of somatic cells in pigs. Additionally, this review examines the multiple roles of apoptosis and summarizes recent progress in porcine pluripotent cells." @default.
- W2519697816 created "2016-09-23" @default.
- W2519697816 creator A5055828187 @default.
- W2519697816 creator A5086987446 @default.
- W2519697816 date "2016-09-12" @default.
- W2519697816 modified "2023-10-08" @default.
- W2519697816 title "Apoptosis in Porcine Pluripotent Cells: From ICM to iPSCs" @default.
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- W2519697816 doi "https://doi.org/10.3390/ijms17091533" @default.
- W2519697816 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5037808" @default.
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