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- W2519902590 abstract "It is most often considered that scalp EEG can only see extended cortical generators, of the order of 6–10 cm2. It has now become clear that in some situations it is possible for the scalp EEG to see generators that are much smaller. It is primarily a question of signal to noise ratio. For a spontaneous epileptic spike, the signal is the spike and the noise is the EEG background. The spike has to be significantly larger than the spontaneous EEG (maybe 100 μV) to be identifiable as a spike. To generate such a spike requires indeed a large fraction of cortex. In the context of an evoked potential, the signal is the evoked potential and the noise is the averaged background; with enough averaging it can be reduced to a fraction of a microvolt and then a signal of 5 μV can become very visible; it may require a much smaller generator (maybe 1 cm2) to generate such a potential. The situation may be similar for High Frequency Oscillations: the noise at high frequencies is very low and even a spontaneous oscillation of 5 μV may be easily identifiable; its generation may only require a very small generator." @default.
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- W2519902590 date "2016-03-01" @default.
- W2519902590 modified "2023-09-27" @default.
- W2519902590 title "EEG can sometimes see very small generators" @default.
- W2519902590 doi "https://doi.org/10.1016/j.clinph.2015.11.161" @default.
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