FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2519904306> ?p ?o ?g. }

• W2519904306 endingPage "e0162805" @default.
• W2519904306 startingPage "e0162805" @default.
• W2519904306 abstract "Longitudinal twin studies on long term conservation of individual metabolic phenotypes can help to explore the genetic and environmental basis in maintaining metabolic homeostasis and metabolic health. We performed a longitudinal twin study on 12 metabolic phenotypes from Danish twins followed up for 12 years and Chinese twins traced for 7 years. The study covered a relatively large sample of 502 pairs of Danish adult twins with a mean age at intake of 38 years and a total of 181 Chinese adult twin pairs with a mean baseline age of 39.5 years. Bivariate twin models were fitted to the longitudinal measurements taken at two time points (at baseline and follow-up) to estimate the genetic and environmental contributions to phenotype variation and correlation at and between the two time points. High genetic components in the regulation of intra-individual phenotype correlation or stability over time were estimated in both Danish (h2>0.75 except fasting blood glucose) and Chinese (h2>0.72 except blood pressure) twins; moderate to high genetic contribution to phenotype variation at the two time points were also estimated except for the low genetic regulation on glucose in Danish and on blood pressure in Chinese twins. Meanwhile the bivariate twin models estimated shared environmental contributions to the variance and covariance in fasting blood glucose in Danish twins, and in systolic and diastolic blood pressure, low and high density lipoprotein cholesterol in Chinese twins. Overall, our longitudinal twin study on long-term stability of metabolic phenotypes in Danish and Chinese twins identified a common pattern of high genetic control over phenotype conservation, and at the same time revealed population-specific patterns of genetic and common environmental regulation on the variance as well as covariance of glucose and blood pressure." @default.
• W2519904306 created "2016-09-23" @default.
• W2519904306 creator A5012426139 @default.
• W2519904306 creator A5013779874 @default.
• W2519904306 creator A5014389043 @default.
• W2519904306 creator A5021109428 @default.
• W2519904306 creator A5024816031 @default.
• W2519904306 creator A5029586809 @default.
• W2519904306 creator A5077569828 @default.
• W2519904306 creator A5087352941 @default.
• W2519904306 creator A5091155937 @default.
• W2519904306 date "2016-09-12" @default.
• W2519904306 modified "2023-09-22" @default.
• W2519904306 title "Longitudinal Investigation into Genetics in the Conservation of Metabolic Phenotypes in Danish and Chinese Twins" @default.
• W2519904306 cites W1547853743 @default.
• W2519904306 cites W1976046065 @default.
• W2519904306 cites W1984407806 @default.
• W2519904306 cites W1988632548 @default.
• W2519904306 cites W2007333570 @default.
• W2519904306 cites W2018289193 @default.
• W2519904306 cites W2044002866 @default.
• W2519904306 cites W2051972088 @default.
• W2519904306 cites W2053330729 @default.
• W2519904306 cites W2054447040 @default.
• W2519904306 cites W2063686029 @default.
• W2519904306 cites W2109232798 @default.
• W2519904306 cites W2110615618 @default.
• W2519904306 cites W2119947818 @default.
• W2519904306 cites W2120833963 @default.
• W2519904306 cites W2123452207 @default.
• W2519904306 cites W2138461593 @default.
• W2519904306 cites W2141078657 @default.
• W2519904306 cites W2142635246 @default.
• W2519904306 cites W2145895489 @default.
• W2519904306 cites W2153382267 @default.
• W2519904306 cites W2155774933 @default.
• W2519904306 cites W2160506573 @default.
• W2519904306 cites W2171817236 @default.
• W2519904306 cites W2272242940 @default.
• W2519904306 doi "https://doi.org/10.1371/journal.pone.0162805" @default.
• W2519904306 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5019416" @default.
• W2519904306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27618179" @default.
• W2519904306 hasPublicationYear "2016" @default.
• W2519904306 type Work @default.
• W2519904306 sameAs 2519904306 @default.
• W2519904306 citedByCount "4" @default.
• W2519904306 countsByYear W25199043062019 @default.
• W2519904306 countsByYear W25199043062020 @default.
• W2519904306 countsByYear W25199043062023 @default.
• W2519904306 crossrefType "journal-article" @default.
• W2519904306 hasAuthorship W2519904306A5012426139 @default.
• W2519904306 hasAuthorship W2519904306A5013779874 @default.
• W2519904306 hasAuthorship W2519904306A5014389043 @default.
• W2519904306 hasAuthorship W2519904306A5021109428 @default.
• W2519904306 hasAuthorship W2519904306A5024816031 @default.
• W2519904306 hasAuthorship W2519904306A5029586809 @default.
• W2519904306 hasAuthorship W2519904306A5077569828 @default.
• W2519904306 hasAuthorship W2519904306A5087352941 @default.
• W2519904306 hasAuthorship W2519904306A5091155937 @default.
• W2519904306 hasBestOaLocation W25199043061 @default.
• W2519904306 hasConcept C104317684 @default.
• W2519904306 hasConcept C105795698 @default.
• W2519904306 hasConcept C127716648 @default.
• W2519904306 hasConcept C134018914 @default.
• W2519904306 hasConcept C138885662 @default.
• W2519904306 hasConcept C142724271 @default.
• W2519904306 hasConcept C161890455 @default.
• W2519904306 hasConcept C164622146 @default.
• W2519904306 hasConcept C169594400 @default.
• W2519904306 hasConcept C2777895361 @default.
• W2519904306 hasConcept C33923547 @default.
• W2519904306 hasConcept C41895202 @default.
• W2519904306 hasConcept C54355233 @default.
• W2519904306 hasConcept C64341305 @default.
• W2519904306 hasConcept C68873052 @default.
• W2519904306 hasConcept C71924100 @default.
• W2519904306 hasConcept C84393581 @default.
• W2519904306 hasConcept C86803240 @default.
• W2519904306 hasConceptScore W2519904306C104317684 @default.
• W2519904306 hasConceptScore W2519904306C105795698 @default.
• W2519904306 hasConceptScore W2519904306C127716648 @default.
• W2519904306 hasConceptScore W2519904306C134018914 @default.
• W2519904306 hasConceptScore W2519904306C138885662 @default.
• W2519904306 hasConceptScore W2519904306C142724271 @default.
• W2519904306 hasConceptScore W2519904306C161890455 @default.
• W2519904306 hasConceptScore W2519904306C164622146 @default.
• W2519904306 hasConceptScore W2519904306C169594400 @default.
• W2519904306 hasConceptScore W2519904306C2777895361 @default.
• W2519904306 hasConceptScore W2519904306C33923547 @default.
• W2519904306 hasConceptScore W2519904306C41895202 @default.
• W2519904306 hasConceptScore W2519904306C54355233 @default.
• W2519904306 hasConceptScore W2519904306C64341305 @default.
• W2519904306 hasConceptScore W2519904306C68873052 @default.
• W2519904306 hasConceptScore W2519904306C71924100 @default.
• W2519904306 hasConceptScore W2519904306C84393581 @default.
• W2519904306 hasConceptScore W2519904306C86803240 @default.
• W2519904306 hasFunder F4320309763 @default.
• W2519904306 hasFunder F4320320870 @default.

• next