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- W2520029322 abstract "Background: Brain Natriuretic Peptide (BNP) has established roles in managing patients with heart failure (HF). Currently, BNP testing is laboratory-based and turnaround time can delay patient management. Point-of-care testing (POCT) potentially allows efficient integration of BNP results with clinical decision-making. The aim of this study was to assess the utility of two POC devices in a HF clinic. Methods: Two POCT devices (A/B) were evaluated to test BNP as part of usual clinical care. DeviceA: venous blood samples were sent for laboratory analysis (Lab-BNP) and capillary samples for POCT (POCT-BNP). DeviceB: capillary and venous samples were obtained. Data analysis: a) consistency between BNP results based on reference levels used in HF management; b) correlation between results. Results: For DeviceA, there was consistency between labBNP and POCT-BNP for 14/20 patients. For the remaining six: one elderly patient with CKD had POCT-BNP inconsistent with lab-BNP, 4 had instrument errors and one had no Lab-BNP performed. For DeviceB, 10 patients were evaluated, there was excellent correlation between capillary and venous BNP (r = 0.97), all of the paired results were similar for utility in HF management. Conclusion: DeviceA, BNP results were similar to laboratory results regarding clinical utility. However DeviceA was unable to integrate data into the hospital systems. DeviceB integrates with hospital systems and has other clinical indications and we have shown excellent correlation between capillary and venous samples. Ease of use with POCT-BNP allows for rapid patient assessment in a HF clinic." @default.
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- W2520029322 date "2015-01-01" @default.
- W2520029322 modified "2023-09-26" @default.
- W2520029322 title "Evaluation of point-of-care testing for brain natriuretic peptide in the out-patient clinic" @default.
- W2520029322 doi "https://doi.org/10.1016/j.hlc.2015.04.072" @default.
- W2520029322 hasPublicationYear "2015" @default.
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