Matches in SemOpenAlex for { <https://semopenalex.org/work/W2520031818> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2520031818 endingPage "e125" @default.
- W2520031818 startingPage "e125" @default.
- W2520031818 abstract "Objective: To evaluate the effect of valsartan treatment on cerebrovascular reactivity (CVR) and arterial stiffness in hypertensive patients with rheumatoid arthritis (RA). Design and Method: Investigation of CVR and arterial stiffness, 24-h ambulatory blood pressure (BP) monitoring were performed in 34 hypertensive patients with RA (male/female 1/33, age 61 [54; 64] years, systolic/diastolic BP 142 [131; 149]/79 [77; 90] mmHg) before (W0) and after 24 weeks valsartan treatment (W24). Valsartan administered 40–320 mg per day. CVR was evaluated by bilateral transcranial Doppler sonography of the middle cerebral arteries (MCA) in hypercapnia (HC). We measured MCA time average maximal blood flow velocity (TAMX), peak systolic velocity (Vps) at baseline, during 2 min inhalation of the 4% mixture of carbonic gas with air (CO2) and during 3 min recovery phase. Arterial stiffness was assessed by the cardio-ankle vascular index (CAVI). Values are presented as Me [25; 75 percentiles]. Results: Before treatment (W0), MCA TAMX, Vps were increased during 2 minutes of CO2 inhalation, but did not return to baseline values in the recovery phase (Figure). Valsartan normalized both systolic and diastolic BP since the first month (P < 0.01). MCA TAMX and Vps did not differ significantly during CO2 inhalation between W0 and W24. Values of MCA blood flow velocities were significantly lower after valsartan treatment compared with W0 in the 3–5 minutes recovery period (P < 0.02). After valsartan treatment (W24), CAVI decreased from 8.1 [6.7; 10.5] to 7.9 [6.7; 11.6] (P < 0.01). Conclusions: Valsartan treatment improved arterial stiffness and CVR in hypertensive patients with RA by normalizing the MCA blood flow velocities in the recovery phase of CO2 test." @default.
- W2520031818 created "2016-09-23" @default.
- W2520031818 creator A5007689997 @default.
- W2520031818 creator A5023219490 @default.
- W2520031818 creator A5038096326 @default.
- W2520031818 creator A5040959619 @default.
- W2520031818 creator A5056954948 @default.
- W2520031818 creator A5066523889 @default.
- W2520031818 creator A5087083891 @default.
- W2520031818 date "2016-09-01" @default.
- W2520031818 modified "2023-09-25" @default.
- W2520031818 title "PS 02-80 THE EFFECT OF VALSARTAN TREATMENT ON CEREBROVASCULAR REACTIVITY AND ARTERAL STIFFNESS IN HYPERTENSIVE PATIENTS WITH RHEUMATOID ARTHRITIS" @default.
- W2520031818 doi "https://doi.org/10.1097/01.hjh.0000500207.62080.f6" @default.
- W2520031818 hasPublicationYear "2016" @default.
- W2520031818 type Work @default.
- W2520031818 sameAs 2520031818 @default.
- W2520031818 citedByCount "0" @default.
- W2520031818 crossrefType "journal-article" @default.
- W2520031818 hasAuthorship W2520031818A5007689997 @default.
- W2520031818 hasAuthorship W2520031818A5023219490 @default.
- W2520031818 hasAuthorship W2520031818A5038096326 @default.
- W2520031818 hasAuthorship W2520031818A5040959619 @default.
- W2520031818 hasAuthorship W2520031818A5056954948 @default.
- W2520031818 hasAuthorship W2520031818A5066523889 @default.
- W2520031818 hasAuthorship W2520031818A5087083891 @default.
- W2520031818 hasConcept C126322002 @default.
- W2520031818 hasConcept C164705383 @default.
- W2520031818 hasConcept C191616109 @default.
- W2520031818 hasConcept C2775850156 @default.
- W2520031818 hasConcept C2776954882 @default.
- W2520031818 hasConcept C2777387769 @default.
- W2520031818 hasConcept C42219234 @default.
- W2520031818 hasConcept C57900726 @default.
- W2520031818 hasConcept C71924100 @default.
- W2520031818 hasConcept C84393581 @default.
- W2520031818 hasConceptScore W2520031818C126322002 @default.
- W2520031818 hasConceptScore W2520031818C164705383 @default.
- W2520031818 hasConceptScore W2520031818C191616109 @default.
- W2520031818 hasConceptScore W2520031818C2775850156 @default.
- W2520031818 hasConceptScore W2520031818C2776954882 @default.
- W2520031818 hasConceptScore W2520031818C2777387769 @default.
- W2520031818 hasConceptScore W2520031818C42219234 @default.
- W2520031818 hasConceptScore W2520031818C57900726 @default.
- W2520031818 hasConceptScore W2520031818C71924100 @default.
- W2520031818 hasConceptScore W2520031818C84393581 @default.
- W2520031818 hasIssue "Supplement 1" @default.
- W2520031818 hasLocation W25200318181 @default.
- W2520031818 hasOpenAccess W2520031818 @default.
- W2520031818 hasPrimaryLocation W25200318181 @default.
- W2520031818 hasRelatedWork W1963978109 @default.
- W2520031818 hasRelatedWork W1988111918 @default.
- W2520031818 hasRelatedWork W2023225611 @default.
- W2520031818 hasRelatedWork W2045583390 @default.
- W2520031818 hasRelatedWork W2046139196 @default.
- W2520031818 hasRelatedWork W2081556299 @default.
- W2520031818 hasRelatedWork W2272595692 @default.
- W2520031818 hasRelatedWork W2330231912 @default.
- W2520031818 hasRelatedWork W2398964630 @default.
- W2520031818 hasRelatedWork W343305083 @default.
- W2520031818 hasVolume "34" @default.
- W2520031818 isParatext "false" @default.
- W2520031818 isRetracted "false" @default.
- W2520031818 magId "2520031818" @default.
- W2520031818 workType "article" @default.