FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2520046616> ?p ?o ?g. }

• W2520046616 endingPage "2043" @default.
• W2520046616 startingPage "2039" @default.
• W2520046616 abstract "Background/purpose Total parenteral nutrition (TPN) has been reported to be associated with mucosal atrophy of the small intestine. Ghrelin has hormonal, orexigenic, and metabolic activities. We investigated whether ghrelin improved intestinal mucosal atrophy using a TPN-supported rat model. Methods Rats underwent jugular vein catheterization and were divided into four groups: TPN alone (TPN), TPN plus low-dose ghrelin (TPNLG), TPN plus high-dose ghrelin (TPNHG), and oral feeding with normal chow (OF). Ghrelin was administered continuously at dosages of 10 or 50 μg/kg/day. On day 6 rats were euthanized, and the small intestine was harvested and divided into the jejunum and ileum. Then the villus height (VH) and crypt depth (CD) were evaluated. Results The jejunal and ileal VH and CD in the TPN group were significantly decreased compared with those in the OF group. TPNHG improved only VH of the jejunum. TPNLG improved VH and CD of the jejunum and CD of the ileum. The improvement of TPNLG was significantly stronger than that in CD of the jejunum and ileum. Conclusions TPN was more strongly associated with mucosal atrophy in the jejunum than in the ileum. Low-dose intravenous administration of ghrelin improved TPN-associated intestinal mucosal atrophy more effectively than high-dose administration." @default.
• W2520046616 created "2016-09-23" @default.
• W2520046616 creator A5000075337 @default.
• W2520046616 creator A5003554514 @default.
• W2520046616 creator A5004399255 @default.
• W2520046616 creator A5037769750 @default.
• W2520046616 creator A5045933469 @default.
• W2520046616 creator A5062814574 @default.
• W2520046616 creator A5070607736 @default.
• W2520046616 creator A5073013616 @default.
• W2520046616 creator A5078309958 @default.
• W2520046616 creator A5086933017 @default.
• W2520046616 creator A5089761965 @default.
• W2520046616 date "2016-12-01" @default.
• W2520046616 modified "2023-09-25" @default.
• W2520046616 title "Ghrelin improves intestinal mucosal atrophy during parenteral nutrition: An experimental study" @default.
• W2520046616 cites W1970202875 @default.
• W2520046616 cites W1972417331 @default.
• W2520046616 cites W1973022658 @default.
• W2520046616 cites W1980266698 @default.
• W2520046616 cites W1983399908 @default.
• W2520046616 cites W1988468478 @default.
• W2520046616 cites W2020063935 @default.
• W2520046616 cites W2027813981 @default.
• W2520046616 cites W2031432117 @default.
• W2520046616 cites W2042247989 @default.
• W2520046616 cites W2051592195 @default.
• W2520046616 cites W2051693095 @default.
• W2520046616 cites W2073248213 @default.
• W2520046616 cites W2079459104 @default.
• W2520046616 cites W2139789471 @default.
• W2520046616 cites W2158908687 @default.
• W2520046616 cites W2163865122 @default.
• W2520046616 cites W2296616853 @default.
• W2520046616 cites W2346582744 @default.
• W2520046616 cites W268970733 @default.
• W2520046616 doi "https://doi.org/10.1016/j.jpedsurg.2016.09.035" @default.
• W2520046616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27832865" @default.
• W2520046616 hasPublicationYear "2016" @default.
• W2520046616 type Work @default.
• W2520046616 sameAs 2520046616 @default.
• W2520046616 citedByCount "12" @default.
• W2520046616 countsByYear W25200466162016 @default.
• W2520046616 countsByYear W25200466162018 @default.
• W2520046616 countsByYear W25200466162020 @default.
• W2520046616 countsByYear W25200466162021 @default.
• W2520046616 countsByYear W25200466162022 @default.
• W2520046616 countsByYear W25200466162023 @default.
• W2520046616 crossrefType "journal-article" @default.
• W2520046616 hasAuthorship W2520046616A5000075337 @default.
• W2520046616 hasAuthorship W2520046616A5003554514 @default.
• W2520046616 hasAuthorship W2520046616A5004399255 @default.
• W2520046616 hasAuthorship W2520046616A5037769750 @default.
• W2520046616 hasAuthorship W2520046616A5045933469 @default.
• W2520046616 hasAuthorship W2520046616A5062814574 @default.
• W2520046616 hasAuthorship W2520046616A5070607736 @default.
• W2520046616 hasAuthorship W2520046616A5073013616 @default.
• W2520046616 hasAuthorship W2520046616A5078309958 @default.
• W2520046616 hasAuthorship W2520046616A5086933017 @default.
• W2520046616 hasAuthorship W2520046616A5089761965 @default.
• W2520046616 hasConcept C126322002 @default.
• W2520046616 hasConcept C131793682 @default.
• W2520046616 hasConcept C134018914 @default.
• W2520046616 hasConcept C2776366702 @default.
• W2520046616 hasConcept C2777226302 @default.
• W2520046616 hasConcept C2777882243 @default.
• W2520046616 hasConcept C2779357093 @default.
• W2520046616 hasConcept C2781172350 @default.
• W2520046616 hasConcept C71315377 @default.
• W2520046616 hasConcept C71924100 @default.
• W2520046616 hasConcept C78722104 @default.
• W2520046616 hasConcept C90924648 @default.
• W2520046616 hasConceptScore W2520046616C126322002 @default.
• W2520046616 hasConceptScore W2520046616C131793682 @default.
• W2520046616 hasConceptScore W2520046616C134018914 @default.
• W2520046616 hasConceptScore W2520046616C2776366702 @default.
• W2520046616 hasConceptScore W2520046616C2777226302 @default.
• W2520046616 hasConceptScore W2520046616C2777882243 @default.
• W2520046616 hasConceptScore W2520046616C2779357093 @default.
• W2520046616 hasConceptScore W2520046616C2781172350 @default.
• W2520046616 hasConceptScore W2520046616C71315377 @default.
• W2520046616 hasConceptScore W2520046616C71924100 @default.
• W2520046616 hasConceptScore W2520046616C78722104 @default.
• W2520046616 hasConceptScore W2520046616C90924648 @default.
• W2520046616 hasFunder F4320334764 @default.
• W2520046616 hasIssue "12" @default.
• W2520046616 hasLocation W25200466161 @default.
• W2520046616 hasLocation W25200466162 @default.
• W2520046616 hasOpenAccess W2520046616 @default.
• W2520046616 hasPrimaryLocation W25200466161 @default.
• W2520046616 hasRelatedWork W1965572178 @default.
• W2520046616 hasRelatedWork W2003577251 @default.
• W2520046616 hasRelatedWork W2029765733 @default.
• W2520046616 hasRelatedWork W2126643606 @default.
• W2520046616 hasRelatedWork W2127596209 @default.
• W2520046616 hasRelatedWork W2140569197 @default.
• W2520046616 hasRelatedWork W2296616853 @default.
• W2520046616 hasRelatedWork W2377334663 @default.

• next