Matches in SemOpenAlex for { <https://semopenalex.org/work/W2520160229> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2520160229 abstract "Summary Metastasis is a complex, multistep biological process, involving a multitude of genes and biomolecules. Despite the successful therapeutic management of breast cancer, including surgery, chemotherapy and radiation therapy, that can control primary tumor growth, metastatic disease remains the greatest clinical challenge in oncology, as these methods are still not very effective in preventing relapses or in the management of breast cancer metastases. The knowledge of its mechanisms is still fragmentary and needs to be broadened in order to improve our therapeutic approach and influence on the long-term control of breast cancer progression. Despite the constant progress in understanding of breast cancer progression, it remains a major health problem around the world. Novel therapeutic modalities are being tested and developed, but the incidence and mortality rates are still frightening. In this paper, we review selected aspects of breast cancer metastasis, including the metastatic cascade and models of dissemination, tumor angiogenesis, disaggregation and migration of cells from the primary tumor, breaking the vascular wall, adaptation to a new environment, organotropism and dormant cells. The interactions between cancer cells and normal host cells contributing significantly to the metastatic cascade are highlighted, and a wide range of signaling and stimulating biomolecules and genes involved in the process are introduced." @default.
- W2520160229 created "2016-09-23" @default.
- W2520160229 creator A5029387701 @default.
- W2520160229 creator A5073131855 @default.
- W2520160229 date "2015-01-01" @default.
- W2520160229 modified "2023-09-24" @default.
- W2520160229 title "Breast cancer metastasis - insight into selected molecular mechanisms of the phenomenon Przerzutowanie w raku piersi - analiza wybranych mechanizmów molekularnych zjawiska" @default.
- W2520160229 cites W1495945591 @default.
- W2520160229 cites W1520425169 @default.
- W2520160229 cites W1964081206 @default.
- W2520160229 cites W1974182660 @default.
- W2520160229 cites W1974511120 @default.
- W2520160229 cites W1980588116 @default.
- W2520160229 cites W1985727076 @default.
- W2520160229 cites W1993497779 @default.
- W2520160229 cites W1997782804 @default.
- W2520160229 cites W1998277522 @default.
- W2520160229 cites W2000000541 @default.
- W2520160229 cites W2001439351 @default.
- W2520160229 cites W2013107571 @default.
- W2520160229 cites W2022233074 @default.
- W2520160229 cites W2033363278 @default.
- W2520160229 cites W2037761545 @default.
- W2520160229 cites W2065716393 @default.
- W2520160229 cites W2070291618 @default.
- W2520160229 cites W2070913528 @default.
- W2520160229 cites W2072889522 @default.
- W2520160229 cites W2075780259 @default.
- W2520160229 cites W2080232352 @default.
- W2520160229 cites W2092868756 @default.
- W2520160229 cites W2108241429 @default.
- W2520160229 cites W2117692326 @default.
- W2520160229 cites W2120294151 @default.
- W2520160229 cites W2147354890 @default.
- W2520160229 cites W2152393981 @default.
- W2520160229 cites W2156323704 @default.
- W2520160229 cites W2156734818 @default.
- W2520160229 cites W2160928966 @default.
- W2520160229 cites W2165200432 @default.
- W2520160229 cites W2172083228 @default.
- W2520160229 cites W3021664385 @default.
- W2520160229 hasPublicationYear "2015" @default.
- W2520160229 type Work @default.
- W2520160229 sameAs 2520160229 @default.
- W2520160229 citedByCount "0" @default.
- W2520160229 crossrefType "journal-article" @default.
- W2520160229 hasAuthorship W2520160229A5029387701 @default.
- W2520160229 hasAuthorship W2520160229A5073131855 @default.
- W2520160229 hasConcept C121608353 @default.
- W2520160229 hasConcept C126322002 @default.
- W2520160229 hasConcept C143998085 @default.
- W2520160229 hasConcept C2775930923 @default.
- W2520160229 hasConcept C2779013556 @default.
- W2520160229 hasConcept C2779134260 @default.
- W2520160229 hasConcept C2780283643 @default.
- W2520160229 hasConcept C2780394083 @default.
- W2520160229 hasConcept C502942594 @default.
- W2520160229 hasConcept C509974204 @default.
- W2520160229 hasConcept C530470458 @default.
- W2520160229 hasConcept C71924100 @default.
- W2520160229 hasConceptScore W2520160229C121608353 @default.
- W2520160229 hasConceptScore W2520160229C126322002 @default.
- W2520160229 hasConceptScore W2520160229C143998085 @default.
- W2520160229 hasConceptScore W2520160229C2775930923 @default.
- W2520160229 hasConceptScore W2520160229C2779013556 @default.
- W2520160229 hasConceptScore W2520160229C2779134260 @default.
- W2520160229 hasConceptScore W2520160229C2780283643 @default.
- W2520160229 hasConceptScore W2520160229C2780394083 @default.
- W2520160229 hasConceptScore W2520160229C502942594 @default.
- W2520160229 hasConceptScore W2520160229C509974204 @default.
- W2520160229 hasConceptScore W2520160229C530470458 @default.
- W2520160229 hasConceptScore W2520160229C71924100 @default.
- W2520160229 hasLocation W25201602291 @default.
- W2520160229 hasOpenAccess W2520160229 @default.
- W2520160229 hasPrimaryLocation W25201602291 @default.
- W2520160229 hasRelatedWork W1493306338 @default.
- W2520160229 hasRelatedWork W1494807148 @default.
- W2520160229 hasRelatedWork W1535292446 @default.
- W2520160229 hasRelatedWork W1966190875 @default.
- W2520160229 hasRelatedWork W1997782804 @default.
- W2520160229 hasRelatedWork W2080862417 @default.
- W2520160229 hasRelatedWork W2138427498 @default.
- W2520160229 hasRelatedWork W2328198526 @default.
- W2520160229 hasRelatedWork W2791650045 @default.
- W2520160229 hasRelatedWork W2964429753 @default.
- W2520160229 hasRelatedWork W3031184646 @default.
- W2520160229 hasRelatedWork W3121455534 @default.
- W2520160229 hasRelatedWork W3147186692 @default.
- W2520160229 hasRelatedWork W3159065019 @default.
- W2520160229 hasRelatedWork W3162894314 @default.
- W2520160229 hasRelatedWork W3178367817 @default.
- W2520160229 hasRelatedWork W3190184148 @default.
- W2520160229 hasRelatedWork W3190605754 @default.
- W2520160229 hasRelatedWork W3192634983 @default.
- W2520160229 hasRelatedWork W2314634970 @default.
- W2520160229 isParatext "false" @default.
- W2520160229 isRetracted "false" @default.
- W2520160229 magId "2520160229" @default.
- W2520160229 workType "article" @default.