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• W2520258885 abstract "2717 Objectives Treatment of inoperative liver cancer and liver metastases using Yttrium-90 (Y90) microspheres is of growing interest in nuclear medicine with different options available for therapy. A glass microsphere, known as TheraSphere, or a resin bead known as SIR-Sphere are currently available as therapy options. Although both are used for the same type of treatment, the setup, delivery, and radiation exposure for the technologist involved are different. This study is a comparison of the workflow efficiency and the radiation dose exposure for the technologist between TheraSphere and SIR-Sphere. Methods Multiple TheraSphere and SIR-Sphere cases were observed and three specific events were timed and recorded. These specific events included: technologist time in the hot lab preparing the dose and paperwork for delivery to IR, delivery of the Y90 microspheres to the patient by the doctor, and technologist time in IR surveying staff in and out of room while delivery of dose and the survey of the room after the patient is complete. The times of each event were averaged and compared to evaluate workflow efficiencies. To evaluate radiation exposure for the technologist, a standard Radex radiation dosimeter (typically included with SIR-Spheres or TheraSpheres kits) and a nanoDOT thermoluminescent dosimeter was worn for each case individually. Values were recorded, normalized to patient dose, and compared for each therapy option. Results The time for each specific event was less for the TheraSphere’s workflow than for SIR-Spheres. The average times for each recorded event for SIR-Sphere preparation was 25.5 minutes. The average times for the TheraSpheres workflow was 18.7 minutes. Both dosimeters showed no additional radiation above control values for TheraSphere cases while SIR-Sphere cases were measurably higher on both dosimeters. Use of TheraSpheres was observed to result in an approximate 6% reduction in technologist dose compared to similar cases using SIR-spheres. Conclusions When comparing the two types of microspheres used for treatment, this study has shown that TheraSphere offers improved workflow efficiency and the lowest radiation dose for a technologist. The treatment doses delivered to the patients during both types of therapies were similar in activity, so the increase in the radiation dose when using SIR-Spheres is more than likely due to having to draw the patient dose from an initial bulk dose of 100 mCi. Because of this bulk dose, however, SIR-Spheres did show an advantage for physicians to be able to change or split the dose the same day as treatment where with TheraSphere that is not an option as the dose is already preformulated and ready for delivery." @default.
• W2520258885 created "2016-09-23" @default.
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• W2520258885 date "2016-05-01" @default.
• W2520258885 modified "2023-09-26" @default.
• W2520258885 title "Comparison of Workflow Efficiency and Technologist Radiation Exposure when using TheraSphere and SIR-Sphere Y90 microspheres for liver cancer therapy." @default.
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