FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2520281036> ?p ?o ?g. }

• W2520281036 endingPage "34" @default.
• W2520281036 startingPage "27" @default.
• W2520281036 abstract "Recombinant chicken prolactin, expressed in Escherichia coli as an unfolded protein, was successfully refolded and purified to homogeneity as a monomeric protein. Its biological activity was evidenced by its ability to interact with rabbit prolactin receptor extracellular domain and stimulate prolactin receptor-mediated proliferation in three cell types possessing mammalian prolactin receptors. Chicken prolactin activity in those assays was 20-100-fold lower than that of mammalian lactogenic hormones, likely due to lower affinity for mammalian prolactin receptors and not to improper refolding, because in two homologous bioassays, chicken prolactin activity was equal to or higher than that of ovine prolactin and the CD spectra of chicken and human prolactin were almost identical. Our results using seven mammalian lactogenic hormones from five species in three bioassays revealed the major role of species specificity in testing biological activity in vitro. Heterologous bioassays may be misleading and homologous assays are strongly recommended for predicting the activity of species-specific lactogenic hormones in vivo." @default.
• W2520281036 created "2016-09-23" @default.
• W2520281036 creator A5009127168 @default.
• W2520281036 creator A5022415049 @default.
• W2520281036 creator A5030337880 @default.
• W2520281036 creator A5046669455 @default.
• W2520281036 creator A5057720896 @default.
• W2520281036 creator A5076153388 @default.
• W2520281036 date "2017-01-01" @default.
• W2520281036 modified "2023-09-23" @default.
• W2520281036 title "Comparison of in vitro bioactivity of chicken prolactin and mammalian lactogenic hormones" @default.
• W2520281036 cites W1494888628 @default.
• W2520281036 cites W1543539965 @default.
• W2520281036 cites W1568255768 @default.
• W2520281036 cites W1645369990 @default.
• W2520281036 cites W1951084542 @default.
• W2520281036 cites W1964360649 @default.
• W2520281036 cites W1976781089 @default.
• W2520281036 cites W1983893485 @default.
• W2520281036 cites W1996777842 @default.
• W2520281036 cites W1998081632 @default.
• W2520281036 cites W2007350106 @default.
• W2520281036 cites W2016906199 @default.
• W2520281036 cites W2027656976 @default.
• W2520281036 cites W2039672509 @default.
• W2520281036 cites W2039767157 @default.
• W2520281036 cites W2043304903 @default.
• W2520281036 cites W2043623751 @default.
• W2520281036 cites W2052871283 @default.
• W2520281036 cites W2054213011 @default.
• W2520281036 cites W2073068364 @default.
• W2520281036 cites W2078468557 @default.
• W2520281036 cites W2079894076 @default.
• W2520281036 cites W2083450715 @default.
• W2520281036 cites W2096809941 @default.
• W2520281036 cites W2100837269 @default.
• W2520281036 cites W2103753256 @default.
• W2520281036 cites W2113103296 @default.
• W2520281036 cites W2122444086 @default.
• W2520281036 cites W2144954853 @default.
• W2520281036 cites W2151097772 @default.
• W2520281036 cites W2162715208 @default.
• W2520281036 cites W4238548516 @default.
• W2520281036 doi "https://doi.org/10.1016/j.ygcen.2016.09.008" @default.
• W2520281036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27641684" @default.
• W2520281036 hasPublicationYear "2017" @default.
• W2520281036 type Work @default.
• W2520281036 sameAs 2520281036 @default.
• W2520281036 citedByCount "5" @default.
• W2520281036 countsByYear W25202810362017 @default.
• W2520281036 countsByYear W25202810362018 @default.
• W2520281036 countsByYear W25202810362021 @default.
• W2520281036 crossrefType "journal-article" @default.
• W2520281036 hasAuthorship W2520281036A5009127168 @default.
• W2520281036 hasAuthorship W2520281036A5022415049 @default.
• W2520281036 hasAuthorship W2520281036A5030337880 @default.
• W2520281036 hasAuthorship W2520281036A5046669455 @default.
• W2520281036 hasAuthorship W2520281036A5057720896 @default.
• W2520281036 hasAuthorship W2520281036A5076153388 @default.
• W2520281036 hasConcept C104317684 @default.
• W2520281036 hasConcept C104488531 @default.
• W2520281036 hasConcept C116073593 @default.
• W2520281036 hasConcept C126322002 @default.
• W2520281036 hasConcept C134018914 @default.
• W2520281036 hasConcept C170493617 @default.
• W2520281036 hasConcept C202751555 @default.
• W2520281036 hasConcept C207001950 @default.
• W2520281036 hasConcept C2779064019 @default.
• W2520281036 hasConcept C2780115692 @default.
• W2520281036 hasConcept C2781031661 @default.
• W2520281036 hasConcept C28406088 @default.
• W2520281036 hasConcept C40767141 @default.
• W2520281036 hasConcept C54355233 @default.
• W2520281036 hasConcept C55493867 @default.
• W2520281036 hasConcept C71315377 @default.
• W2520281036 hasConcept C71924100 @default.
• W2520281036 hasConcept C86803240 @default.
• W2520281036 hasConceptScore W2520281036C104317684 @default.
• W2520281036 hasConceptScore W2520281036C104488531 @default.
• W2520281036 hasConceptScore W2520281036C116073593 @default.
• W2520281036 hasConceptScore W2520281036C126322002 @default.
• W2520281036 hasConceptScore W2520281036C134018914 @default.
• W2520281036 hasConceptScore W2520281036C170493617 @default.
• W2520281036 hasConceptScore W2520281036C202751555 @default.
• W2520281036 hasConceptScore W2520281036C207001950 @default.
• W2520281036 hasConceptScore W2520281036C2779064019 @default.
• W2520281036 hasConceptScore W2520281036C2780115692 @default.
• W2520281036 hasConceptScore W2520281036C2781031661 @default.
• W2520281036 hasConceptScore W2520281036C28406088 @default.
• W2520281036 hasConceptScore W2520281036C40767141 @default.
• W2520281036 hasConceptScore W2520281036C54355233 @default.
• W2520281036 hasConceptScore W2520281036C55493867 @default.
• W2520281036 hasConceptScore W2520281036C71315377 @default.
• W2520281036 hasConceptScore W2520281036C71924100 @default.
• W2520281036 hasConceptScore W2520281036C86803240 @default.
• W2520281036 hasLocation W25202810361 @default.
• W2520281036 hasLocation W25202810362 @default.
• W2520281036 hasOpenAccess W2520281036 @default.

• next