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- W2520313144 abstract "Objectives There is increasing evidence that epilepsy might alter the brain connectivities. We investigated the changes in the brain connectivity in children with benign childhood epilepsy with centro-temporal spikes. Methods High density EEG data recorded from 8 patients and age-matched 9 controls with eyes closed. For controls five segments and for patients five with- and without-spike were randomly selected for further analysis. The phase locking value was calculated for all pairwise combination of channels within five frequency bands (™, , 〈, ®1 and ®2). We computed degree and small-world parameters- clustering coefficient (C) and path length (L). Results We observed higher degrees in the regions involved in the generation of spikes in all frequency bands. Patients showed reduced connectivity values at the occipital and right frontal region in 〈 band. The “small-world” features (high C and low L) were lost in patients. The epileptic brain network was more ordered (high C, high L) in lower frequency, but switched into a random mode (low C, low L) in higher frequencies. Conclusion These findings show that the epileptic brain network might be disrupted not only at the epileptic zone but also in other brain regions. The benign epileptic brain networks also showed ordered and random topology in lower and higher frequencies respectively." @default.
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- W2520313144 date "2016-03-01" @default.
- W2520313144 modified "2023-09-26" @default.
- W2520313144 title "ID 234 – Brain network analysis of EEG functional connectivity in patients with benign childhood epilepsy with centro-temporal spikes" @default.
- W2520313144 doi "https://doi.org/10.1016/j.clinph.2015.11.198" @default.
- W2520313144 hasPublicationYear "2016" @default.
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