Matches in SemOpenAlex for { <https://semopenalex.org/work/W2521243225> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2521243225 endingPage "30" @default.
- W2521243225 startingPage "726" @default.
- W2521243225 abstract "To investigate the changes in the proportion and function of peripheral CD4(+)LAP(+)regulatory T cells (CD4(+)LAP(+)Treg cells) in children with asthma, as well as the role of CD4(+)LAP(+)Treg cells in the pathogenesis of asthma.A total of 75 children who were diagnosed with asthma from March 2014 to September 2015 were enrolled as study subjects, and according to their conditions, they were divided into acute-stage asthma group (40 children) and remission-stage asthma group (35 patients). Another 30 children who underwent physical examination were enrolled as the healthy control group. Flow cytometry was used to determine the percentage of peripheral CD4(+)LAP(+)Treg cells, and [(3)H]-thymidine incorporation assay was performed to analyze the immunosuppression of CD4(+)LAP(+)Treg cells in each group.The acute-stage asthma group showed significant reductions in the proportion of CD4(+)LAP(+)Treg cells compared with the remission-stage asthma group and the healthy control group (2.0%±1.0% vs 4.1%±2.4%/4.6%±3.0%; P<0.05). The acute-stage asthma group also showed a significant reduction in the immunosuppression rate of CD4(+)LAP(+)Treg cells compared with the remission-stage asthma group and the healthy control group (21%±4% vs 55%±9%/62%±11%; P<0.05).In children with asthma, the reduction in the number and inhibitory function of peripheral CD4(+)LAP(+)Treg cells may be involved in the pathogenesis of asthma." @default.
- W2521243225 created "2016-09-30" @default.
- W2521243225 creator A5053519636 @default.
- W2521243225 creator A5068707358 @default.
- W2521243225 creator A5070383988 @default.
- W2521243225 date "2016-08-01" @default.
- W2521243225 modified "2023-09-27" @default.
- W2521243225 title "[Changes in proportion and function of peripheral CD4(+)LAP(+) regulatory T cells in children with asthma]." @default.
- W2521243225 cites W1558298429 @default.
- W2521243225 cites W1810971862 @default.
- W2521243225 cites W1818689388 @default.
- W2521243225 cites W1965888819 @default.
- W2521243225 cites W1969021940 @default.
- W2521243225 cites W2000790539 @default.
- W2521243225 cites W2024260354 @default.
- W2521243225 cites W2027746633 @default.
- W2521243225 cites W2046575161 @default.
- W2521243225 cites W2061372463 @default.
- W2521243225 cites W2116645352 @default.
- W2521243225 cites W2132516980 @default.
- W2521243225 cites W2166484453 @default.
- W2521243225 cites W2330375590 @default.
- W2521243225 cites W2368440474 @default.
- W2521243225 cites W2397248706 @default.
- W2521243225 cites W2473289815 @default.
- W2521243225 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7399523" @default.
- W2521243225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27530790" @default.
- W2521243225 hasPublicationYear "2016" @default.
- W2521243225 type Work @default.
- W2521243225 sameAs 2521243225 @default.
- W2521243225 citedByCount "0" @default.
- W2521243225 crossrefType "journal-article" @default.
- W2521243225 hasAuthorship W2521243225A5053519636 @default.
- W2521243225 hasAuthorship W2521243225A5068707358 @default.
- W2521243225 hasAuthorship W2521243225A5070383988 @default.
- W2521243225 hasConcept C126322002 @default.
- W2521243225 hasConcept C203014093 @default.
- W2521243225 hasConcept C2776042228 @default.
- W2521243225 hasConcept C2780252810 @default.
- W2521243225 hasConcept C2780942790 @default.
- W2521243225 hasConcept C46762472 @default.
- W2521243225 hasConcept C553184892 @default.
- W2521243225 hasConcept C71924100 @default.
- W2521243225 hasConceptScore W2521243225C126322002 @default.
- W2521243225 hasConceptScore W2521243225C203014093 @default.
- W2521243225 hasConceptScore W2521243225C2776042228 @default.
- W2521243225 hasConceptScore W2521243225C2780252810 @default.
- W2521243225 hasConceptScore W2521243225C2780942790 @default.
- W2521243225 hasConceptScore W2521243225C46762472 @default.
- W2521243225 hasConceptScore W2521243225C553184892 @default.
- W2521243225 hasConceptScore W2521243225C71924100 @default.
- W2521243225 hasIssue "8" @default.
- W2521243225 hasLocation W25212432251 @default.
- W2521243225 hasOpenAccess W2521243225 @default.
- W2521243225 hasPrimaryLocation W25212432251 @default.
- W2521243225 hasRelatedWork W2027383039 @default.
- W2521243225 hasRelatedWork W204558573 @default.
- W2521243225 hasRelatedWork W2351226947 @default.
- W2521243225 hasRelatedWork W2359199095 @default.
- W2521243225 hasRelatedWork W2375180626 @default.
- W2521243225 hasRelatedWork W2394033620 @default.
- W2521243225 hasRelatedWork W3029429637 @default.
- W2521243225 hasRelatedWork W3030129740 @default.
- W2521243225 hasRelatedWork W3030164439 @default.
- W2521243225 hasRelatedWork W3032540778 @default.
- W2521243225 hasVolume "18" @default.
- W2521243225 isParatext "false" @default.
- W2521243225 isRetracted "false" @default.
- W2521243225 magId "2521243225" @default.
- W2521243225 workType "article" @default.