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- W2521541004 abstract "Polyaromatic hydrocarbons (PAH`S) have be monitored using intercalation of double stranded DNA. Three approaches have been examined. The first, an electrochemical method uses an electroactive intercalating agent. When intercalated into DNA it cannot transfer electrons to an electrode. When displaced by a PAH, it can be detected electrochemically. The second method utilizes fluorescence polarization. A fluorescent intercalating agent, when intercalated into DNA will show increased polarization. When displaced by a competing PAH, a decrease in polarization is observed. The third technique involves evanescent wave technology. Double stranded DNA in close proximity to the wave guide will show a decreased fluorescence when a fluorescent intercalator is displaced by a PAH. Each of these techniques will be described and examples of results presented." @default.
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- W2521541004 date "1995-12-01" @default.
- W2521541004 modified "2023-09-24" @default.
- W2521541004 title "Detection of polyaromatic hydrocarbons using DNA intercalation" @default.
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