FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2521773766> ?p ?o ?g. }

• W2521773766 endingPage "411" @default.
• W2521773766 startingPage "403" @default.
• W2521773766 abstract "Objectives We sought to determine if a durable bilayer implant composed of trabecular metal with autologous periosteum on top would be suitable to reconstitute large osteochondral defects. This design would allow for secure implant fixation, subsequent integration and remodeling. Materials and Methods Adult sheep were randomly assigned to one of three groups (n = 8/group): 1. trabecular metal/periosteal graft (TMPG), 2. trabecular metal (TM), 3. empty defect (ED). Cartilage and bone healing were assessed macroscopically, biochemically (type II collagen, sulfated glycosaminoglycan (sGAG) and double-stranded DNA (dsDNA) content) and histologically. Results At 16 weeks post-operatively, histological scores amongst treatment groups were not statistically different (TMPG: overall 12.7, cartilage 8.6, bone 4.1; TM: overall 14.2, cartilage 9.5, bone 4.9; ED: overall 13.6, cartilage 9.1, bone 4.5). Metal scaffolds were incorporated into the surrounding bone, both in TM and TMPG. The sGAG yield was lower in the neo-cartilage regions compared with the articular cartilage (AC) controls (TMPG 20.8/AC 39.5, TM 25.6/AC 33.3, ED 32.2/AC 40.2 µg sGAG/1 mg respectively), with statistical significance being achieved for the TMPG group (p < 0.05). Hypercellularity of the neo-cartilage was found in TM and ED, as the dsDNA content was significantly higher (p < 0.05) compared with contralateral AC controls (TM 126.7/AC 71.1, ED 99.3/AC 62.8 ng dsDNA/1 mg). The highest type II collagen content was found in neo-cartilage after TM compared with TMPG and ED (TM 60%/TMPG 40%/ED 39%). Inter-treatment differences were not significant. Conclusions TM is a highly suitable material for the reconstitution of osseous defects. TM enables excellent bony ingrowth and fast integration. However, combined with autologous periosteum, such a biocomposite failed to promote satisfactory neo-cartilage formation. Cite this article: E. H. Mrosek, H-W. Chung, J. S. Fitzsimmons, S. W. O’Driscoll, G. G. Reinholz, J. C. Schagemann. Porous tantalum biocomposites for osteochondral defect repair: A follow-up study in a sheep model. Bone Joint J 2016;5:403–411. DOI: 10.1302/2046-3758.59.BJR-2016-0070.R1." @default.
• W2521773766 created "2016-09-30" @default.
• W2521773766 creator A5015783193 @default.
• W2521773766 creator A5040003493 @default.
• W2521773766 creator A5043077739 @default.
• W2521773766 creator A5044613491 @default.
• W2521773766 creator A5060689620 @default.
• W2521773766 creator A5087690787 @default.
• W2521773766 date "2016-09-01" @default.
• W2521773766 modified "2023-09-29" @default.
• W2521773766 title "Porous tantalum biocomposites for osteochondral defect repair" @default.
• W2521773766 cites W1946911025 @default.
• W2521773766 cites W1964744563 @default.
• W2521773766 cites W1967462133 @default.
• W2521773766 cites W1975471671 @default.
• W2521773766 cites W1977368578 @default.
• W2521773766 cites W1978778471 @default.
• W2521773766 cites W1980800152 @default.
• W2521773766 cites W1980959628 @default.
• W2521773766 cites W1984155551 @default.
• W2521773766 cites W1991169694 @default.
• W2521773766 cites W1993818347 @default.
• W2521773766 cites W1995659229 @default.
• W2521773766 cites W1996315992 @default.
• W2521773766 cites W2001694585 @default.
• W2521773766 cites W2007600326 @default.
• W2521773766 cites W2017765680 @default.
• W2521773766 cites W2017986522 @default.
• W2521773766 cites W2029247294 @default.
• W2521773766 cites W2039488563 @default.
• W2521773766 cites W2040522261 @default.
• W2521773766 cites W205089275 @default.
• W2521773766 cites W2050911192 @default.
• W2521773766 cites W2057459297 @default.
• W2521773766 cites W2057743821 @default.
• W2521773766 cites W2058605450 @default.
• W2521773766 cites W2061073787 @default.
• W2521773766 cites W2061799524 @default.
• W2521773766 cites W2065008385 @default.
• W2521773766 cites W2065230666 @default.
• W2521773766 cites W2067079430 @default.
• W2521773766 cites W2077144860 @default.
• W2521773766 cites W2086318913 @default.
• W2521773766 cites W2088564623 @default.
• W2521773766 cites W2090521629 @default.
• W2521773766 cites W2092341472 @default.
• W2521773766 cites W2106057396 @default.
• W2521773766 cites W2117171195 @default.
• W2521773766 cites W2133009750 @default.
• W2521773766 cites W2134017201 @default.
• W2521773766 cites W2137232985 @default.
• W2521773766 cites W2165569726 @default.
• W2521773766 cites W2242656930 @default.
• W2521773766 cites W2292815294 @default.
• W2521773766 cites W4250595858 @default.
• W2521773766 cites W4297755929 @default.
• W2521773766 doi "https://doi.org/10.1302/2046-3758.59.bjr-2016-0070.r1" @default.
• W2521773766 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5037966" @default.
• W2521773766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27660334" @default.
• W2521773766 hasPublicationYear "2016" @default.
• W2521773766 type Work @default.
• W2521773766 sameAs 2521773766 @default.
• W2521773766 citedByCount "10" @default.
• W2521773766 countsByYear W25217737662017 @default.
• W2521773766 countsByYear W25217737662018 @default.
• W2521773766 countsByYear W25217737662019 @default.
• W2521773766 countsByYear W25217737662020 @default.
• W2521773766 countsByYear W25217737662021 @default.
• W2521773766 countsByYear W25217737662022 @default.
• W2521773766 crossrefType "journal-article" @default.
• W2521773766 hasAuthorship W2521773766A5015783193 @default.
• W2521773766 hasAuthorship W2521773766A5040003493 @default.
• W2521773766 hasAuthorship W2521773766A5043077739 @default.
• W2521773766 hasAuthorship W2521773766A5044613491 @default.
• W2521773766 hasAuthorship W2521773766A5060689620 @default.
• W2521773766 hasAuthorship W2521773766A5087690787 @default.
• W2521773766 hasBestOaLocation W25217737661 @default.
• W2521773766 hasConcept C105702510 @default.
• W2521773766 hasConcept C136229726 @default.
• W2521773766 hasConcept C141071460 @default.
• W2521773766 hasConcept C153074725 @default.
• W2521773766 hasConcept C185592680 @default.
• W2521773766 hasConcept C192562407 @default.
• W2521773766 hasConcept C2780550940 @default.
• W2521773766 hasConcept C2781411149 @default.
• W2521773766 hasConcept C55493867 @default.
• W2521773766 hasConcept C71924100 @default.
• W2521773766 hasConceptScore W2521773766C105702510 @default.
• W2521773766 hasConceptScore W2521773766C136229726 @default.
• W2521773766 hasConceptScore W2521773766C141071460 @default.
• W2521773766 hasConceptScore W2521773766C153074725 @default.
• W2521773766 hasConceptScore W2521773766C185592680 @default.
• W2521773766 hasConceptScore W2521773766C192562407 @default.
• W2521773766 hasConceptScore W2521773766C2780550940 @default.
• W2521773766 hasConceptScore W2521773766C2781411149 @default.
• W2521773766 hasConceptScore W2521773766C55493867 @default.
• W2521773766 hasConceptScore W2521773766C71924100 @default.
• W2521773766 hasIssue "9" @default.

• next