FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2521781140> ?p ?o ?g. }

• W2521781140 endingPage "3023" @default.
• W2521781140 startingPage "3017" @default.
• W2521781140 abstract "Meningococcal septic shock is associated with profound vasoplegia, early and severe myocardial dysfunction, and extended skin necrosis responsible for a specific clinical entity designated purpura fulminans (PF). PF represents 90% of fatal meningococcal infections. One characteristic of meningococcal PF is the myocardial dysfunction that occurs in the early phase of sepsis. Furthermore, hemodynamic studies have shown that the prognosis of meningococcal sepsis is directly related to the degree of impairment of cardiac contractility during the initial phase of the disease. To gain insight into a potential interaction of Neisseria meningitidis with the myocardial microvasculature, we modified a previously described humanized mouse model by grafting human myocardial tissue to SCID mice. We then infected the grafted mice with N. meningitides Using the humanized SCID mouse model, we demonstrated that N. meningitidis targets the human myocardial tissue vasculature, leading to the formation of blood thrombi, infectious vasculitis, and vascular leakage. These results suggest a novel mechanism of myocardial injury in the course of severe N. meningitidis sepsis that is likely to participate in primary myocardial dysfunction." @default.
• W2521781140 created "2016-09-30" @default.
• W2521781140 creator A5006894459 @default.
• W2521781140 creator A5012275661 @default.
• W2521781140 creator A5012704377 @default.
• W2521781140 creator A5023873767 @default.
• W2521781140 creator A5054481926 @default.
• W2521781140 creator A5074681722 @default.
• W2521781140 creator A5085040774 @default.
• W2521781140 creator A5088673157 @default.
• W2521781140 date "2016-10-01" @default.
• W2521781140 modified "2023-10-15" @default.
• W2521781140 title "Experimental Evidence of Bacterial Colonization of Human Coronary Microvasculature and Myocardial Tissue during Meningococcemia" @default.
• W2521781140 cites W1821714266 @default.
• W2521781140 cites W1836738234 @default.
• W2521781140 cites W1897825357 @default.
• W2521781140 cites W1968472831 @default.
• W2521781140 cites W1969868956 @default.
• W2521781140 cites W1994159005 @default.
• W2521781140 cites W1997058721 @default.
• W2521781140 cites W2005626356 @default.
• W2521781140 cites W2006919847 @default.
• W2521781140 cites W2021002606 @default.
• W2521781140 cites W2043513395 @default.
• W2521781140 cites W2065198767 @default.
• W2521781140 cites W2066183003 @default.
• W2521781140 cites W2078042237 @default.
• W2521781140 cites W2088106005 @default.
• W2521781140 cites W2089338345 @default.
• W2521781140 cites W2104978347 @default.
• W2521781140 cites W2105898520 @default.
• W2521781140 cites W2117037612 @default.
• W2521781140 cites W2119772828 @default.
• W2521781140 cites W2120399837 @default.
• W2521781140 cites W2122396701 @default.
• W2521781140 cites W2133410828 @default.
• W2521781140 cites W2134866355 @default.
• W2521781140 cites W2157958976 @default.
• W2521781140 cites W2167636398 @default.
• W2521781140 cites W4210712363 @default.
• W2521781140 doi "https://doi.org/10.1128/iai.00420-16" @default.
• W2521781140 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5038069" @default.
• W2521781140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27481255" @default.
• W2521781140 hasPublicationYear "2016" @default.
• W2521781140 type Work @default.
• W2521781140 sameAs 2521781140 @default.
• W2521781140 citedByCount "6" @default.
• W2521781140 countsByYear W25217811402018 @default.
• W2521781140 countsByYear W25217811402019 @default.
• W2521781140 countsByYear W25217811402020 @default.
• W2521781140 countsByYear W25217811402021 @default.
• W2521781140 crossrefType "journal-article" @default.
• W2521781140 hasAuthorship W2521781140A5006894459 @default.
• W2521781140 hasAuthorship W2521781140A5012275661 @default.
• W2521781140 hasAuthorship W2521781140A5012704377 @default.
• W2521781140 hasAuthorship W2521781140A5023873767 @default.
• W2521781140 hasAuthorship W2521781140A5054481926 @default.
• W2521781140 hasAuthorship W2521781140A5074681722 @default.
• W2521781140 hasAuthorship W2521781140A5085040774 @default.
• W2521781140 hasAuthorship W2521781140A5088673157 @default.
• W2521781140 hasBestOaLocation W25217811401 @default.
• W2521781140 hasConcept C126322002 @default.
• W2521781140 hasConcept C141071460 @default.
• W2521781140 hasConcept C203014093 @default.
• W2521781140 hasConcept C2776645655 @default.
• W2521781140 hasConcept C2777628635 @default.
• W2521781140 hasConcept C2777969115 @default.
• W2521781140 hasConcept C2778384902 @default.
• W2521781140 hasConcept C2778458888 @default.
• W2521781140 hasConcept C39133596 @default.
• W2521781140 hasConcept C523546767 @default.
• W2521781140 hasConcept C54355233 @default.
• W2521781140 hasConcept C71924100 @default.
• W2521781140 hasConcept C86803240 @default.
• W2521781140 hasConceptScore W2521781140C126322002 @default.
• W2521781140 hasConceptScore W2521781140C141071460 @default.
• W2521781140 hasConceptScore W2521781140C203014093 @default.
• W2521781140 hasConceptScore W2521781140C2776645655 @default.
• W2521781140 hasConceptScore W2521781140C2777628635 @default.
• W2521781140 hasConceptScore W2521781140C2777969115 @default.
• W2521781140 hasConceptScore W2521781140C2778384902 @default.
• W2521781140 hasConceptScore W2521781140C2778458888 @default.
• W2521781140 hasConceptScore W2521781140C39133596 @default.
• W2521781140 hasConceptScore W2521781140C523546767 @default.
• W2521781140 hasConceptScore W2521781140C54355233 @default.
• W2521781140 hasConceptScore W2521781140C71924100 @default.
• W2521781140 hasConceptScore W2521781140C86803240 @default.
• W2521781140 hasIssue "10" @default.
• W2521781140 hasLocation W25217811401 @default.
• W2521781140 hasLocation W25217811402 @default.
• W2521781140 hasLocation W25217811403 @default.
• W2521781140 hasLocation W25217811404 @default.
• W2521781140 hasLocation W25217811405 @default.
• W2521781140 hasLocation W25217811406 @default.
• W2521781140 hasOpenAccess W2521781140 @default.
• W2521781140 hasPrimaryLocation W25217811401 @default.
• W2521781140 hasRelatedWork W2058155525 @default.
• W2521781140 hasRelatedWork W2088301809 @default.

• next