FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2521783885> ?p ?o ?g. }

• W2521783885 endingPage "1749" @default.
• W2521783885 startingPage "1739" @default.
• W2521783885 abstract "Protein translation can be affected by changes in the secondary structure of mRNA. The dinQ gene in Escherichia coli encodes a primary transcript (+1) that is inert to translation. Ribonucleolytic removal of the 44 first nucleotides converts the +1 transcript into a translationally active form, but the mechanism behind this structural change is unknown. Here we present experimental evidence for a mechanism where alternative RNA secondary structures in the two dinQ mRNA variants affect translation initiation by mediating opening or closing of the ribosome binding sequence. This structural switch is determined by alternative interactions of four sequence elements within the dinQ mRNA and also by the agrB antisense RNA. Additionally, the structural conformation of +1 dinQ suggests a locking mechanism comprised of an RNA stem that both stabilizes and prevents translation initiation from the full-length dinQ transcript. BLAST search and multiple sequence alignments define a new family of dinQ -like genes widespread in Enterobacteriaceae with close RNA sequence similarities in their 5′ untranslated regions. Thus, it appears that a whole new family of genes is regulated by the same mechanism of alternative secondary RNA structures." @default.
• W2521783885 created "2016-09-30" @default.
• W2521783885 creator A5001769847 @default.
• W2521783885 creator A5021161802 @default.
• W2521783885 creator A5026160980 @default.
• W2521783885 creator A5042050127 @default.
• W2521783885 date "2016-09-20" @default.
• W2521783885 modified "2023-09-23" @default.
• W2521783885 title "Mutually exclusive RNA secondary structures regulate translation initiation of DinQ in <i>Escherichia coli</i>" @default.
• W2521783885 cites W1606605658 @default.
• W2521783885 cites W1711307584 @default.
• W2521783885 cites W1916496494 @default.
• W2521783885 cites W1939540784 @default.
• W2521783885 cites W1963945004 @default.
• W2521783885 cites W1977298702 @default.
• W2521783885 cites W1981765089 @default.
• W2521783885 cites W1982165499 @default.
• W2521783885 cites W1995909556 @default.
• W2521783885 cites W2007887595 @default.
• W2521783885 cites W2016461937 @default.
• W2521783885 cites W2020375786 @default.
• W2521783885 cites W2024354549 @default.
• W2521783885 cites W2046374424 @default.
• W2521783885 cites W2046646094 @default.
• W2521783885 cites W2061673063 @default.
• W2521783885 cites W2067258168 @default.
• W2521783885 cites W2067540509 @default.
• W2521783885 cites W2072670062 @default.
• W2521783885 cites W2075118834 @default.
• W2521783885 cites W2076937215 @default.
• W2521783885 cites W2083750892 @default.
• W2521783885 cites W2092422591 @default.
• W2521783885 cites W2098889266 @default.
• W2521783885 cites W2112732905 @default.
• W2521783885 cites W2116881995 @default.
• W2521783885 cites W2118902684 @default.
• W2521783885 cites W2121350645 @default.
• W2521783885 cites W2132046933 @default.
• W2521783885 cites W2136970762 @default.
• W2521783885 cites W2141157874 @default.
• W2521783885 cites W2143407915 @default.
• W2521783885 cites W2146346646 @default.
• W2521783885 cites W2152207030 @default.
• W2521783885 cites W2163120292 @default.
• W2521783885 doi "https://doi.org/10.1261/rna.058461.116" @default.
• W2521783885 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5066626" @default.
• W2521783885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27651528" @default.
• W2521783885 hasPublicationYear "2016" @default.
• W2521783885 type Work @default.
• W2521783885 sameAs 2521783885 @default.
• W2521783885 citedByCount "20" @default.
• W2521783885 countsByYear W25217838852017 @default.
• W2521783885 countsByYear W25217838852018 @default.
• W2521783885 countsByYear W25217838852019 @default.
• W2521783885 countsByYear W25217838852020 @default.
• W2521783885 countsByYear W25217838852021 @default.
• W2521783885 countsByYear W25217838852023 @default.
• W2521783885 crossrefType "journal-article" @default.
• W2521783885 hasAuthorship W2521783885A5001769847 @default.
• W2521783885 hasAuthorship W2521783885A5021161802 @default.
• W2521783885 hasAuthorship W2521783885A5026160980 @default.
• W2521783885 hasAuthorship W2521783885A5042050127 @default.
• W2521783885 hasBestOaLocation W25217838851 @default.
• W2521783885 hasConcept C104317684 @default.
• W2521783885 hasConcept C105580179 @default.
• W2521783885 hasConcept C114847915 @default.
• W2521783885 hasConcept C12464233 @default.
• W2521783885 hasConcept C126142528 @default.
• W2521783885 hasConcept C149364088 @default.
• W2521783885 hasConcept C194993378 @default.
• W2521783885 hasConcept C4718897 @default.
• W2521783885 hasConcept C54355233 @default.
• W2521783885 hasConcept C55493867 @default.
• W2521783885 hasConcept C62614982 @default.
• W2521783885 hasConcept C67705224 @default.
• W2521783885 hasConcept C70721500 @default.
• W2521783885 hasConcept C85468374 @default.
• W2521783885 hasConcept C86803240 @default.
• W2521783885 hasConcept C88478588 @default.
• W2521783885 hasConcept C89604277 @default.
• W2521783885 hasConceptScore W2521783885C104317684 @default.
• W2521783885 hasConceptScore W2521783885C105580179 @default.
• W2521783885 hasConceptScore W2521783885C114847915 @default.
• W2521783885 hasConceptScore W2521783885C12464233 @default.
• W2521783885 hasConceptScore W2521783885C126142528 @default.
• W2521783885 hasConceptScore W2521783885C149364088 @default.
• W2521783885 hasConceptScore W2521783885C194993378 @default.
• W2521783885 hasConceptScore W2521783885C4718897 @default.
• W2521783885 hasConceptScore W2521783885C54355233 @default.
• W2521783885 hasConceptScore W2521783885C55493867 @default.
• W2521783885 hasConceptScore W2521783885C62614982 @default.
• W2521783885 hasConceptScore W2521783885C67705224 @default.
• W2521783885 hasConceptScore W2521783885C70721500 @default.
• W2521783885 hasConceptScore W2521783885C85468374 @default.
• W2521783885 hasConceptScore W2521783885C86803240 @default.
• W2521783885 hasConceptScore W2521783885C88478588 @default.
• W2521783885 hasConceptScore W2521783885C89604277 @default.
• W2521783885 hasFunder F4320323299 @default.

• next