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• W2522236536 endingPage "11301" @default.
• W2522236536 startingPage "11292" @default.
• W2522236536 abstract "Nanoscale lead dioxide (nPbO2(s)) is a corrosion product formed from the chlorination of lead-containing plumbing materials. This metal oxide nanoparticle (NP) plays a key role in determining lead pollution in drinking water and receiving water bodies. This study uses nPbO2(s) and medaka fish (Oryzias latipes) as surrogates to investigate the aqueous fate and toxicological risk of metal oxide NPs associated with water matrices. The larvae of medaka were treated with solutions containing nPbO2(s) or Pb(II)aq in different water matrices for 7–14 days to investigate the in vivo toxic effects of NPs. Ionic strength enhanced aggregation and sedimentation of nPbO2(s) in water, leading to increased lead contents in fish bodies. However, the presence of dissolved organic matter in water enhanced particle stability and accelerated the lead dissolution, thus changing the bioavailability processes (bioaccessibility) of particles. Oxidative stress response and neurotoxicity in exposed fish was greater for nPbO2(s) solution with increased salinity than dissolved organic matter. We predict the bioavailability processes and toxicity of nPbO2(s) in medaka from the aqueous particle behavior under environmentally relevant exposure conditions. Our investigation suggests a toxicological risk of metal oxide NP pollution in the aquatic environment." @default.
• W2522236536 created "2016-09-30" @default.
• W2522236536 creator A5001681213 @default.
• W2522236536 creator A5004391147 @default.
• W2522236536 creator A5055053759 @default.
• W2522236536 creator A5091706726 @default.
• W2522236536 date "2016-10-04" @default.
• W2522236536 modified "2023-10-15" @default.
• W2522236536 title "Dissolved Organic Matter or Salts Change the Bioavailability Processes and Toxicity of the Nanoscale Tetravalent Lead Corrosion Product PbO₂ to Medaka Fish" @default.
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• W2522236536 doi "https://doi.org/10.1021/acs.est.6b02072" @default.
• W2522236536 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27648669" @default.
• W2522236536 hasPublicationYear "2016" @default.
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