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- W2522753313 abstract "Introduction: Vertebroplasty is used to treat painful osteoporotic vertebral fractures, and involves transpedicular injection of bone cement into the fractured vertebral body. During injection, the fluid cement begins to “harden” to a solid, enabling it to support mechanical load. But the mechanical efficacy of vertebroplasty can be improved by using cements which disperse evenly throughout the vertebral body during injection (1). We hypothesise that a better cement dispersion is obtained with cements that have a slower viscosity increase during hardening. We test this using a numerical model. Methods: A computer model mimicking the plate- and rod-like morphologies of cancellous bone was loaded into a commercial fluid dynamics package (CFX). During injection, viscosity increased linearly with time to simulate the hardening behaviour of the cement (2). The rate of viscosity increase was altered to mimic the hardening behaviour of 5 different cements, with the rates of increase chosen to encompass the hardening behaviour of commercial vertebroplasty cements (1). Simulations were run for 13 seconds, with cement injection at 1.5 mm/s. Cement dispersion was quantified by the proportion of marrow replaced by cement during injection. Injection pressure was also recorded. Results: Injection pressure increased with time (p Conclusion: Cements with slower hardening characteristics are dispersed more evenly throughout cancellous bone. Such cements may provide safer and more effective vertebroplasty procedures. Conflicts of Interest: None Source of Funding: Bupa Foundation" @default.
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- W2522753313 date "2011-11-01" @default.
- W2522753313 modified "2023-09-27" @default.
- W2522753313 title "BONE CEMENT DISPERSION DURING VERTEBROPLASTY IS INFLUENCED BY CEMENT HARDENING BEHAVIOUR: A NUMERICAL MODEL" @default.
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