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- W2522877650 abstract "1China Beijing KLX Biosciences. Ltd, China 2Shanghai MabStar. Inc., China 3Daqing Fu Rui Bang Biotech Co. Ltd. China C knowledge endows the chemists with an unlimited ability to synthesize so many non-natural small molecular compounds as drug candidates, but who thought the unbalancing of the earth chemical systems has being accelerated? As for medicine, biologists or doctors rarely think about the “biocompatibility” and “bio-conditionality” based on the relationship among bios (creatures), nature, and non-natural compounds. Our preliminary experiments on the most commonlyused OTC medicines, BENADRYL and TYLENOL, have been made to investigate the eff ects on mouse behaviors and physiology by administrating to the pregnant BALB/c mice through drinking water and with the dosage calculated by the body surface area. A signifi cant autism-like ADHD behavior in 2-3 month age F1 BALB/c mice was recorded on the open fi eld test between the groups of Paracetamol (also known as Acetaminophen, Fortolin, Panodol, Snaplets, Suff erin, Tylenol) taking and the control. Another fi nding is severe fatty liver about 5 months aft er born in all the F1 off -springs of BALB/c mice whose mothers took diphenhydramine during their pregnancy but not in the controls. Th ese may clue to the nosogenesis searching for some current high-incident disorders. Further studies may be conducted to investigate the epigenetic modifi cations and the genetic susceptibility in the following generations. Th e nature is enslaved by bio-conditionality to getting the non-natural compounds from bios, while the bios may follow the law of biocompatibility and limit the synthesis of incompatible compounds in their body (see the sketch map at the end of this abstract). Human might have made an extra power onto bios (including itself) to promote the anagenesis or catagenesis." @default.
- W2522877650 created "2016-09-30" @default.
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- W2522877650 date "2013-07-11" @default.
- W2522877650 modified "2023-09-26" @default.
- W2522877650 title "Biocompatibility and Bioconditionality- A new mirror for current and future medicines" @default.
- W2522877650 hasPublicationYear "2013" @default.
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