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- W2523184439 abstract "Patients with low-grade glioma frequently have brain tumor–related epilepsy, which is more common than in patients with high-grade glioma. Treatment for tumor-associated epilepsy usually comprises a combination of surgery, anti-epileptic drugs (AEDs), chemotherapy, and radiotherapy. Response to tumor-directed treatment is measured primarily by overall survival and progression-free survival. However, seizure frequency has been observed to respond to tumor-directed treatment with chemotherapy or radiotherapy. A review of the current literature regarding seizure assessment for low-grade glioma patients reveals a heterogeneous manner in which seizure response has been reported. There is a need for a systematic approach to seizure assessment and its influence on health-related quality-of-life outcomes in patients enrolled in low-grade glioma therapeutic trials. In view of the need to have an adjunctive metric of tumor response in these patients, a method of seizure assessment as a metric in brain tumor treatment trials is proposed." @default.
- W2523184439 created "2016-09-30" @default.
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- W2523184439 date "2016-09-20" @default.
- W2523184439 modified "2023-10-14" @default.
- W2523184439 title "Seizure control as a new metric in assessing efficacy of tumor treatment in low-grade glioma trials" @default.
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- W2523184439 doi "https://doi.org/10.1093/neuonc/now190" @default.
- W2523184439 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5193028" @default.
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- W2523184439 hasPublicationYear "2016" @default.
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