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• W2523189916 abstract "Twelve new limonoids (khasenegasins O–Z; <b>1</b>–<b>12</b>) with three different kinds of skeletons, including eight mexicanolides, two gedunins, and two andirobins, together with four known limonoids (<b>13</b>–<b>16</b>) were isolated from the seeds of <i>Khaya senegalensis</i>. Their structures were determined by extensive spectroscopic analyses (HR-ESI-MS, 1D/2D NMR), and the absolute configurations of <b>1</b> and <b>2</b> were established by the electronic circular dichroism exciton chirality method. Moreover, a new andirobin-type limonoid (<b>12</b>) showed significant neuroprotective activity against glutamate-induced injury in primary rat cerebellar granule neuronal cells with increased viability of 83.3 ± 6.0 % at 10 µM and 80.3 ± 3.2 % at 1 µM." @default.
• W2523189916 created "2016-09-30" @default.
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• W2523189916 date "2016-09-20" @default.
• W2523189916 modified "2023-10-18" @default.
• W2523189916 title "New Structurally Diverse Limonoids from the Seeds of Khaya senegalensis" @default.
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• W2523189916 doi "https://doi.org/10.1055/s-0042-117114" @default.
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