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- W2523371507 abstract "RIGHT-HANDED SUGARS AND left-handed amino acids characterize life, yet how this selectivity came about is one of the chemical mysteries that surrounds life's origins. Chemists may be a step closer to unraveling that mystery thanks to experiments by graduate student Alan Saghatelian, professor M. Reza Ghadiri, and their colleagues at Scripps Research Institute, La Jolla, Calif. The Scripps chemists have designed a short peptide, 32 amino acids long, that can selectively and efficiently produce homochiral products from a racemic starting mixture of peptide fragments [Nature, 409,797 (2001)}. Others involved in the project are graduate student Yohei Yokobayashi and undergraduate Kathy Soltani. It was supported by NASA's Astrobiology Institute. A small imbalance between Dand L-isomers of biologically important molecules might develop in several ways, Ghadiri notes. However this initial imbalance comes about, you would still need to amplify the effect, he explains. Our work shows for the first time that hom..." @default.
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- W2523371507 date "2001-02-19" @default.
- W2523371507 modified "2023-09-27" @default.
- W2523371507 title "SINGLE-HANDED REPLICATION" @default.
- W2523371507 doi "https://doi.org/10.1021/cen-v079n008.p015" @default.
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