FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2523590939> ?p ?o ?g. }

• W2523590939 abstract "The intravenous anesthetic propofol is a gamma-aminobutyric acid A receptor agonist. Propofol promotes analgesia by depressing nociceptive transmission in peripheral neurons, antagonizing N-methyl-D-aspartate receptors, and activating gamma-aminobutyric acid A receptors in dorsal root ganglion receptor cells. Nevertheless, it remains unclear whether intraoperative propofol causes clinically meaningful postoperative analgesia. We therefore tested the hypothesis that patients anesthetized with sevoflurane require a greater quantity of postoperative opioids (from the end of surgery until the next postoperative morning) than those anesthetized with propofol.With Institutional Review Board and EudraCT Number approval (2009-011038-82) and patients' informed consent, ninety patients scheduled for open vein stripping were randomized to either sevoflurane or propofol anesthesia at the Medical University of Vienna General Hospital and the Danube Hospital, the largest regional hospital in Vienna. Pain was treated with bolus piritramide and patient-controlled morphine hydrochloride. The primary outcome was total opioid use from the end of surgery until the first postoperative morning. For the initial four postoperative hours and on the first postoperative morning, a blinded investigator recorded pain scores on an 11-point Likert verbal response scale.The median [interquartile range] morphine sulfate equivalents were 9.8 [4-19] mg in the sevoflurane group and 10 [6-20] mg in the propofol group. Sevoflurane was not superior to propofol on postoperative opioid consumption, giving a ratio of means of 0.91 (95% interim-adjusted confidence interval [CI], 0.33 to 2.45; P = 0.74). Additionally, no difference in pain scores was found over time between the two groups, with a mean difference on an 11-point scale of 0.20 (95% interim-adjusted CI, -0.36 to 0.73; P = 0.31).Intraoperative sevoflurane did not reduce postoperative analgesia. This finding is consistent with the results in most previous reports. This trial was registered at ClinicalTrials.gov: NCT00712517." @default.
• W2523590939 created "2016-09-30" @default.
• W2523590939 creator A5013690515 @default.
• W2523590939 creator A5027177568 @default.
• W2523590939 creator A5029736560 @default.
• W2523590939 creator A5042996287 @default.
• W2523590939 creator A5064337155 @default.
• W2523590939 creator A5070245346 @default.
• W2523590939 creator A5071628958 @default.
• W2523590939 creator A5074283800 @default.
• W2523590939 creator A5090940061 @default.
• W2523590939 date "2016-09-14" @default.
• W2523590939 modified "2023-10-08" @default.
• W2523590939 title "Opioid use after propofol or sevoflurane anesthesia: a randomized trial" @default.
• W2523590939 cites W1583751109 @default.
• W2523590939 cites W1965729530 @default.
• W2523590939 cites W1965840447 @default.
• W2523590939 cites W1973648347 @default.
• W2523590939 cites W1973811079 @default.
• W2523590939 cites W1983494422 @default.
• W2523590939 cites W2000542353 @default.
• W2523590939 cites W2001639091 @default.
• W2523590939 cites W2018798046 @default.
• W2523590939 cites W2020723984 @default.
• W2523590939 cites W2033596238 @default.
• W2523590939 cites W2068330549 @default.
• W2523590939 cites W2083217606 @default.
• W2523590939 cites W2088359978 @default.
• W2523590939 cites W2089169356 @default.
• W2523590939 cites W2089288824 @default.
• W2523590939 cites W2108983865 @default.
• W2523590939 cites W2122328323 @default.
• W2523590939 cites W2126049444 @default.
• W2523590939 cites W2141633403 @default.
• W2523590939 cites W2150941885 @default.
• W2523590939 cites W2153590489 @default.
• W2523590939 cites W2162174253 @default.
• W2523590939 cites W2616797457 @default.
• W2523590939 cites W4248057390 @default.
• W2523590939 doi "https://doi.org/10.1007/s12630-016-0728-5" @default.
• W2523590939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27638296" @default.
• W2523590939 hasPublicationYear "2016" @default.
• W2523590939 type Work @default.
• W2523590939 sameAs 2523590939 @default.
• W2523590939 citedByCount "5" @default.
• W2523590939 countsByYear W25235909392018 @default.
• W2523590939 countsByYear W25235909392021 @default.
• W2523590939 crossrefType "journal-article" @default.
• W2523590939 hasAuthorship W2523590939A5013690515 @default.
• W2523590939 hasAuthorship W2523590939A5027177568 @default.
• W2523590939 hasAuthorship W2523590939A5029736560 @default.
• W2523590939 hasAuthorship W2523590939A5042996287 @default.
• W2523590939 hasAuthorship W2523590939A5064337155 @default.
• W2523590939 hasAuthorship W2523590939A5070245346 @default.
• W2523590939 hasAuthorship W2523590939A5071628958 @default.
• W2523590939 hasAuthorship W2523590939A5074283800 @default.
• W2523590939 hasAuthorship W2523590939A5090940061 @default.
• W2523590939 hasBestOaLocation W25235909391 @default.
• W2523590939 hasConcept C119060515 @default.
• W2523590939 hasConcept C126322002 @default.
• W2523590939 hasConcept C141071460 @default.
• W2523590939 hasConcept C168563851 @default.
• W2523590939 hasConcept C170493617 @default.
• W2523590939 hasConcept C2776277131 @default.
• W2523590939 hasConcept C2781063702 @default.
• W2523590939 hasConcept C2781072394 @default.
• W2523590939 hasConcept C2781453256 @default.
• W2523590939 hasConcept C42219234 @default.
• W2523590939 hasConcept C71924100 @default.
• W2523590939 hasConceptScore W2523590939C119060515 @default.
• W2523590939 hasConceptScore W2523590939C126322002 @default.
• W2523590939 hasConceptScore W2523590939C141071460 @default.
• W2523590939 hasConceptScore W2523590939C168563851 @default.
• W2523590939 hasConceptScore W2523590939C170493617 @default.
• W2523590939 hasConceptScore W2523590939C2776277131 @default.
• W2523590939 hasConceptScore W2523590939C2781063702 @default.
• W2523590939 hasConceptScore W2523590939C2781072394 @default.
• W2523590939 hasConceptScore W2523590939C2781453256 @default.
• W2523590939 hasConceptScore W2523590939C42219234 @default.
• W2523590939 hasConceptScore W2523590939C71924100 @default.
• W2523590939 hasLocation W25235909391 @default.
• W2523590939 hasLocation W25235909392 @default.
• W2523590939 hasOpenAccess W2523590939 @default.
• W2523590939 hasPrimaryLocation W25235909391 @default.
• W2523590939 hasRelatedWork W1707892628 @default.
• W2523590939 hasRelatedWork W1949708446 @default.
• W2523590939 hasRelatedWork W2021782200 @default.
• W2523590939 hasRelatedWork W2097814416 @default.
• W2523590939 hasRelatedWork W2105597153 @default.
• W2523590939 hasRelatedWork W2111619967 @default.
• W2523590939 hasRelatedWork W2123296629 @default.
• W2523590939 hasRelatedWork W2134558496 @default.
• W2523590939 hasRelatedWork W2142201101 @default.
• W2523590939 hasRelatedWork W2161034334 @default.
• W2523590939 hasRelatedWork W2198503191 @default.
• W2523590939 hasRelatedWork W2468457378 @default.
• W2523590939 hasRelatedWork W2789628307 @default.
• W2523590939 hasRelatedWork W2809644701 @default.
• W2523590939 hasRelatedWork W2944716289 @default.
• W2523590939 hasRelatedWork W2996326194 @default.

• next