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- W2523699384 abstract "Silk fibers spun by silkworms and spiders exhibit exceptional mechanical properties with a unique combination of strength, extensibility and toughness. In contrast, the mechanical properties of regenerated silk materials can be tuned through control of the fabrication process. Here we introduce a biomimetic, all-aqueous process, to obtain bulk regenerated silk-based materials for the fabrication of functionalized orthopedic devices. The silk materials generated in the process replicate the nano-scale structure of natural silk fibers and possess excellent mechanical properties. The biomimetic materials demonstrate excellent machinability, providing a path towards the fabrication of a new family of resorbable orthopedic devices where organic solvents are avoided, thus allowing functionalization with bioactive molecules to promote bone remodeling and integration." @default.
- W2523699384 created "2016-09-30" @default.
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- W2523699384 date "2016-12-01" @default.
- W2523699384 modified "2023-09-27" @default.
- W2523699384 title "Regenerated silk materials for functionalized silk orthopedic devices by mimicking natural processing" @default.
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- W2523699384 doi "https://doi.org/10.1016/j.biomaterials.2016.09.014" @default.
- W2523699384 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5104183" @default.
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