Matches in SemOpenAlex for { <https://semopenalex.org/work/W2523833114> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2523833114 abstract "Introduction. Necrobiosis lipoidica (NL) is a granulomatous skin disease of still only partially known pathogenesis. Microangiopathy is considered as one of the most important processes in NL, and vascular endothelial growth factor (VEGF) and endothelin-1 are strongly involved in it. Recent studies have demonstrated the beneficial therapeutic effect of tumor necrosis factor α (TNF-α) inhibitors in treatment of recalcitrant cases of NL, which is due to the important role of TNF-α in development of inflammation and granulomas in the course of NL. Objective. To assess the serum levels of VEGF, endothelin-1 and TNF-α in NL patients. Material and methods. The study group consisted of 17 patients with NL (mean age 48.22 ±15.99 years), 37 patients with diabetes mellitus (mean age 52.11 ±17.41 years) and 23 healthy volunteers (mean age 44.13 ±9.33 years) as a control group. Serum concentrations of TNF-α, VEGF and endothelin-1 were assessed in all patients with the ELISA test. Results. The TNF-α concentration was statistically lower in the controls when compared to the NL patients and diabetic patients (p 0.05 for all comparisons). Endothelin-1 serum values were under the tested values in most cases; however, statistically more frequently these values were found in the controls than in the NL group (p < 0.05)." @default.
- W2523833114 created "2016-10-07" @default.
- W2523833114 creator A5048034786 @default.
- W2523833114 creator A5054193045 @default.
- W2523833114 creator A5067303031 @default.
- W2523833114 creator A5086993961 @default.
- W2523833114 date "2014-01-01" @default.
- W2523833114 modified "2023-09-27" @default.
- W2523833114 title "Czy proces zapalny odgrywa rolę w patogenezie obumierania tłuszczowatego" @default.
- W2523833114 cites W1966555727 @default.
- W2523833114 cites W1982808990 @default.
- W2523833114 cites W1985712533 @default.
- W2523833114 cites W1990068830 @default.
- W2523833114 cites W1992562127 @default.
- W2523833114 cites W1999647970 @default.
- W2523833114 cites W2002782364 @default.
- W2523833114 cites W2023515397 @default.
- W2523833114 cites W2025359892 @default.
- W2523833114 cites W2048168141 @default.
- W2523833114 cites W2068582926 @default.
- W2523833114 cites W2074808021 @default.
- W2523833114 cites W2076443001 @default.
- W2523833114 cites W2115537688 @default.
- W2523833114 cites W2412041753 @default.
- W2523833114 cites W2419145039 @default.
- W2523833114 cites W2498116163 @default.
- W2523833114 hasPublicationYear "2014" @default.
- W2523833114 type Work @default.
- W2523833114 sameAs 2523833114 @default.
- W2523833114 citedByCount "0" @default.
- W2523833114 crossrefType "journal-article" @default.
- W2523833114 hasAuthorship W2523833114A5048034786 @default.
- W2523833114 hasAuthorship W2523833114A5054193045 @default.
- W2523833114 hasAuthorship W2523833114A5067303031 @default.
- W2523833114 hasAuthorship W2523833114A5086993961 @default.
- W2523833114 hasConcept C126322002 @default.
- W2523833114 hasConcept C134018914 @default.
- W2523833114 hasConcept C144980905 @default.
- W2523833114 hasConcept C149601957 @default.
- W2523833114 hasConcept C167734588 @default.
- W2523833114 hasConcept C170493617 @default.
- W2523833114 hasConcept C17991360 @default.
- W2523833114 hasConcept C203014093 @default.
- W2523833114 hasConcept C2776513394 @default.
- W2523833114 hasConcept C2777025900 @default.
- W2523833114 hasConcept C2780942790 @default.
- W2523833114 hasConcept C3020084786 @default.
- W2523833114 hasConcept C555293320 @default.
- W2523833114 hasConcept C71924100 @default.
- W2523833114 hasConcept C90924648 @default.
- W2523833114 hasConceptScore W2523833114C126322002 @default.
- W2523833114 hasConceptScore W2523833114C134018914 @default.
- W2523833114 hasConceptScore W2523833114C144980905 @default.
- W2523833114 hasConceptScore W2523833114C149601957 @default.
- W2523833114 hasConceptScore W2523833114C167734588 @default.
- W2523833114 hasConceptScore W2523833114C170493617 @default.
- W2523833114 hasConceptScore W2523833114C17991360 @default.
- W2523833114 hasConceptScore W2523833114C203014093 @default.
- W2523833114 hasConceptScore W2523833114C2776513394 @default.
- W2523833114 hasConceptScore W2523833114C2777025900 @default.
- W2523833114 hasConceptScore W2523833114C2780942790 @default.
- W2523833114 hasConceptScore W2523833114C3020084786 @default.
- W2523833114 hasConceptScore W2523833114C555293320 @default.
- W2523833114 hasConceptScore W2523833114C71924100 @default.
- W2523833114 hasConceptScore W2523833114C90924648 @default.
- W2523833114 hasLocation W25238331141 @default.
- W2523833114 hasOpenAccess W2523833114 @default.
- W2523833114 hasPrimaryLocation W25238331141 @default.
- W2523833114 isParatext "false" @default.
- W2523833114 isRetracted "false" @default.
- W2523833114 magId "2523833114" @default.
- W2523833114 workType "article" @default.