FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2523890399> ?p ?o ?g. }

• W2523890399 endingPage "265" @default.
• W2523890399 startingPage "249" @default.
• W2523890399 abstract "Although CF is a genetically transmitted disease, various immunologic phenomena have been documented to occur during its inexorable clinical course. Abundant and abnormally sticky mucous secretions block ducts in the gastrointestinal and respiratory tracts and account for both slowing of mucociliary clearance as well as obstruction, inflammation, and chronic infection. Colonization and infection with P. aeruginosa as well as other strains of bacterial organisms may be responsible for the clinical progression of CF lung disease and have been associated with immune responses that may seem contradictory in nature. Most CF patients demonstrate hyperimmune responses to bacterial antigens such as hypergammaglobulinemia, leukocytosis, increased lymphocyte stimulation, elevated complement levels, and immune complex production. Other CF patients may have hypogammaglobulinemia and still others show a depressed lymphocyte responses to Pseudomonas. Many of the variations in immune responses parallel progression of the chronic obstructive lung disease and its associated state of malnutrition. Classic allergic manifestations may also occur, some of which are IgE medicated such as atopy, reactive airways disease, and a higher prevalence of allergic bronchopulmonary aspergillosis than is seen in any other childhood lung disease. In addition, non--IgE-mediated phenomena in the presence of immune complexes in serum, sputum, and lung tissue have been reported. Treatment of CF is primarily supportive but includes specific measures directed at the control of pulmonary infection, augmentation of mucus clearance, and various nutritional therapies. The use of immunologically boosting or suppressing therapies are currently under investigation in multicenter studies." @default.
• W2523890399 created "2016-10-07" @default.
• W2523890399 creator A5018588402 @default.
• W2523890399 creator A5081804846 @default.
• W2523890399 date "1992-05-01" @default.
• W2523890399 modified "2023-09-25" @default.
• W2523890399 title "IMMUNOLOGIC FEATURES OF THE LUNGS IN CYSTIC FIBROSIS" @default.
• W2523890399 cites W1557653296 @default.
• W2523890399 cites W1638257391 @default.
• W2523890399 cites W1890434927 @default.
• W2523890399 cites W1897469112 @default.
• W2523890399 cites W1902674103 @default.
• W2523890399 cites W1947785372 @default.
• W2523890399 cites W1964540252 @default.
• W2523890399 cites W1971302885 @default.
• W2523890399 cites W1971509223 @default.
• W2523890399 cites W1983872845 @default.
• W2523890399 cites W1986100256 @default.
• W2523890399 cites W1989045338 @default.
• W2523890399 cites W1990256357 @default.
• W2523890399 cites W1990615889 @default.
• W2523890399 cites W1994908472 @default.
• W2523890399 cites W1995249948 @default.
• W2523890399 cites W2007836518 @default.
• W2523890399 cites W2015782994 @default.
• W2523890399 cites W2025220428 @default.
• W2523890399 cites W2026492869 @default.
• W2523890399 cites W2029497320 @default.
• W2523890399 cites W2032776070 @default.
• W2523890399 cites W2038876065 @default.
• W2523890399 cites W2039599894 @default.
• W2523890399 cites W2041507812 @default.
• W2523890399 cites W2046354137 @default.
• W2523890399 cites W2067613052 @default.
• W2523890399 cites W2071041539 @default.
• W2523890399 cites W2073171988 @default.
• W2523890399 cites W2081499639 @default.
• W2523890399 cites W2091653480 @default.
• W2523890399 cites W2097646128 @default.
• W2523890399 cites W2098584309 @default.
• W2523890399 cites W2099885683 @default.
• W2523890399 cites W2102703468 @default.
• W2523890399 cites W2103368195 @default.
• W2523890399 cites W2103973700 @default.
• W2523890399 cites W2115857062 @default.
• W2523890399 cites W2125391335 @default.
• W2523890399 cites W2146251948 @default.
• W2523890399 cites W2161659196 @default.
• W2523890399 cites W2161767713 @default.
• W2523890399 cites W225040943 @default.
• W2523890399 cites W2320919448 @default.
• W2523890399 cites W2339404979 @default.
• W2523890399 doi "https://doi.org/10.1016/s0889-8561(22)00107-2" @default.
• W2523890399 hasPublicationYear "1992" @default.
• W2523890399 type Work @default.
• W2523890399 sameAs 2523890399 @default.
• W2523890399 citedByCount "2" @default.
• W2523890399 crossrefType "journal-article" @default.
• W2523890399 hasAuthorship W2523890399A5018588402 @default.
• W2523890399 hasAuthorship W2523890399A5081804846 @default.
• W2523890399 hasConcept C114682108 @default.
• W2523890399 hasConcept C126322002 @default.
• W2523890399 hasConcept C141105273 @default.
• W2523890399 hasConcept C142724271 @default.
• W2523890399 hasConcept C159654299 @default.
• W2523890399 hasConcept C203014093 @default.
• W2523890399 hasConcept C2776301714 @default.
• W2523890399 hasConcept C2776938444 @default.
• W2523890399 hasConcept C2777697326 @default.
• W2523890399 hasConcept C2777714996 @default.
• W2523890399 hasConcept C2777802486 @default.
• W2523890399 hasConcept C2778871687 @default.
• W2523890399 hasConcept C2779379686 @default.
• W2523890399 hasConcept C2780648854 @default.
• W2523890399 hasConcept C2781069245 @default.
• W2523890399 hasConcept C71924100 @default.
• W2523890399 hasConcept C8891405 @default.
• W2523890399 hasConceptScore W2523890399C114682108 @default.
• W2523890399 hasConceptScore W2523890399C126322002 @default.
• W2523890399 hasConceptScore W2523890399C141105273 @default.
• W2523890399 hasConceptScore W2523890399C142724271 @default.
• W2523890399 hasConceptScore W2523890399C159654299 @default.
• W2523890399 hasConceptScore W2523890399C203014093 @default.
• W2523890399 hasConceptScore W2523890399C2776301714 @default.
• W2523890399 hasConceptScore W2523890399C2776938444 @default.
• W2523890399 hasConceptScore W2523890399C2777697326 @default.
• W2523890399 hasConceptScore W2523890399C2777714996 @default.
• W2523890399 hasConceptScore W2523890399C2777802486 @default.
• W2523890399 hasConceptScore W2523890399C2778871687 @default.
• W2523890399 hasConceptScore W2523890399C2779379686 @default.
• W2523890399 hasConceptScore W2523890399C2780648854 @default.
• W2523890399 hasConceptScore W2523890399C2781069245 @default.
• W2523890399 hasConceptScore W2523890399C71924100 @default.
• W2523890399 hasConceptScore W2523890399C8891405 @default.
• W2523890399 hasIssue "2" @default.
• W2523890399 hasLocation W25238903991 @default.
• W2523890399 hasOpenAccess W2523890399 @default.
• W2523890399 hasPrimaryLocation W25238903991 @default.

• next