FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2524274934> ?p ?o ?g. }

• W2524274934 endingPage "607" @default.
• W2524274934 startingPage "602" @default.
• W2524274934 abstract "Human serum paraoxonase 1 (PON1) is carried by high-density lipoprotein in blood circulation and is shown to be effective in preventing oxidized phospholipids carried by low-density lipoprotein particles, thus it acts as an antioxidant. Polymorphism in this gene has been investigated for many metabolic diseases, but it is not thought to be a genetic risk factor for essential hypertension. The aim of this study was to determine whether there was an association between PON1 gene polymorphisms and concentration with essential hypertension. The study population was comprised of 100 patients with essential hypertension and 100 healthy controls. One promoter region [C(-108)T] and two coding region (Q192R and L55M) polymorphisms in the PON1 gene were genotyped in individuals by using the TaqMan assay. Plasma PON1 concentration in all volunteers was also measured spectrophotometrically by the enzyme-linked immunosorbent assay method. The genotype and allele frequencies of the PON1 C(-108)T polymorphism showed significant differences between the essential hypertensive and control groups (CT vs. CC: p<0.001; T allele vs. C allele: p<0.001). There was no significant difference for the PON1 L55M polymorphism between the groups, while the heterozygote genotype of the PON1 Q192R polymorphism showed significant difference (p = 0.03). The PON1 concentration was also found to be significantly lower in hypertensive patients (p < 0.001). Decline in the level of PON1 gene may be one of the main factors in the development of essential hypertension, and the PON1 C(-108)T polymorphism may have a prognostic value in the patients with essential hypertension." @default.
• W2524274934 created "2016-10-07" @default.
• W2524274934 creator A5002883582 @default.
• W2524274934 creator A5011116271 @default.
• W2524274934 creator A5046157305 @default.
• W2524274934 creator A5068372922 @default.
• W2524274934 creator A5069176550 @default.
• W2524274934 creator A5078115530 @default.
• W2524274934 creator A5085704037 @default.
• W2524274934 date "2016-09-26" @default.
• W2524274934 modified "2023-09-30" @default.
• W2524274934 title "Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension" @default.
• W2524274934 cites W1847322718 @default.
• W2524274934 cites W1965946150 @default.
• W2524274934 cites W1981709271 @default.
• W2524274934 cites W1982201389 @default.
• W2524274934 cites W1997801947 @default.
• W2524274934 cites W1999480713 @default.
• W2524274934 cites W2008600234 @default.
• W2524274934 cites W2013480805 @default.
• W2524274934 cites W2014126308 @default.
• W2524274934 cites W2023368049 @default.
• W2524274934 cites W2030964561 @default.
• W2524274934 cites W2035014901 @default.
• W2524274934 cites W2035772760 @default.
• W2524274934 cites W2037622905 @default.
• W2524274934 cites W2039655118 @default.
• W2524274934 cites W2040309911 @default.
• W2524274934 cites W2055219529 @default.
• W2524274934 cites W2055881144 @default.
• W2524274934 cites W2065634680 @default.
• W2524274934 cites W2104882897 @default.
• W2524274934 cites W2115139514 @default.
• W2524274934 cites W2115848618 @default.
• W2524274934 cites W2135519224 @default.
• W2524274934 cites W2138328421 @default.
• W2524274934 cites W2160780373 @default.
• W2524274934 cites W2225273165 @default.
• W2524274934 cites W2396385885 @default.
• W2524274934 doi "https://doi.org/10.3109/10641963.2016.1174255" @default.
• W2524274934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27668323" @default.
• W2524274934 hasPublicationYear "2016" @default.
• W2524274934 type Work @default.
• W2524274934 sameAs 2524274934 @default.
• W2524274934 citedByCount "14" @default.
• W2524274934 countsByYear W25242749342017 @default.
• W2524274934 countsByYear W25242749342018 @default.
• W2524274934 countsByYear W25242749342019 @default.
• W2524274934 countsByYear W25242749342020 @default.
• W2524274934 countsByYear W25242749342021 @default.
• W2524274934 countsByYear W25242749342022 @default.
• W2524274934 crossrefType "journal-article" @default.
• W2524274934 hasAuthorship W2524274934A5002883582 @default.
• W2524274934 hasAuthorship W2524274934A5011116271 @default.
• W2524274934 hasAuthorship W2524274934A5046157305 @default.
• W2524274934 hasAuthorship W2524274934A5068372922 @default.
• W2524274934 hasAuthorship W2524274934A5069176550 @default.
• W2524274934 hasAuthorship W2524274934A5078115530 @default.
• W2524274934 hasAuthorship W2524274934A5085704037 @default.
• W2524274934 hasConcept C104317684 @default.
• W2524274934 hasConcept C126322002 @default.
• W2524274934 hasConcept C134018914 @default.
• W2524274934 hasConcept C135763542 @default.
• W2524274934 hasConcept C149737253 @default.
• W2524274934 hasConcept C180754005 @default.
• W2524274934 hasConcept C2776151105 @default.
• W2524274934 hasConcept C2776509667 @default.
• W2524274934 hasConcept C2777097880 @default.
• W2524274934 hasConcept C2778242859 @default.
• W2524274934 hasConcept C2908647359 @default.
• W2524274934 hasConcept C37463918 @default.
• W2524274934 hasConcept C37501387 @default.
• W2524274934 hasConcept C54355233 @default.
• W2524274934 hasConcept C71924100 @default.
• W2524274934 hasConcept C76252995 @default.
• W2524274934 hasConcept C84393581 @default.
• W2524274934 hasConcept C86803240 @default.
• W2524274934 hasConcept C99454951 @default.
• W2524274934 hasConceptScore W2524274934C104317684 @default.
• W2524274934 hasConceptScore W2524274934C126322002 @default.
• W2524274934 hasConceptScore W2524274934C134018914 @default.
• W2524274934 hasConceptScore W2524274934C135763542 @default.
• W2524274934 hasConceptScore W2524274934C149737253 @default.
• W2524274934 hasConceptScore W2524274934C180754005 @default.
• W2524274934 hasConceptScore W2524274934C2776151105 @default.
• W2524274934 hasConceptScore W2524274934C2776509667 @default.
• W2524274934 hasConceptScore W2524274934C2777097880 @default.
• W2524274934 hasConceptScore W2524274934C2778242859 @default.
• W2524274934 hasConceptScore W2524274934C2908647359 @default.
• W2524274934 hasConceptScore W2524274934C37463918 @default.
• W2524274934 hasConceptScore W2524274934C37501387 @default.
• W2524274934 hasConceptScore W2524274934C54355233 @default.
• W2524274934 hasConceptScore W2524274934C71924100 @default.
• W2524274934 hasConceptScore W2524274934C76252995 @default.
• W2524274934 hasConceptScore W2524274934C84393581 @default.
• W2524274934 hasConceptScore W2524274934C86803240 @default.
• W2524274934 hasConceptScore W2524274934C99454951 @default.
• W2524274934 hasIssue "7" @default.

• next