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• W2524276812 abstract "Cassia fistula (Fabaceae) is one of the most commonly used medicinal plants for its antimalarial and antimicrobialactivities. So far, safety of the plant fruit seed as a traditional medicine has not been well investigated. Therefore, theeffect of C. fistula seeds on sub-chronic hepatic toxicity in chicks fed with 30-50 mg/kg methanolic extract of thefruit seeds, for 7-21 days, was investigated. The protective effect of C. fistula on organs and the hematological andbiochemical parameters were examined. At 40 mg/kg dose of C. fistula to chicks showed a non-significant decrease incount of RBCs and other serological values, presumably through a provoked hemolysis of RBCs and/or toxicity of theplant. However, a significant reduction in liver function enzymes (ALP, ALT and AST) urea, and creatinine levels withan increase in plasma protein reflected on its hepato-renal protection. Only nominal pathological lesions were observedin microscopic examination of the chick’s hepatic tissues. We propose that C. fistula fruit seeds are hepatoprotective andrenoprotective." @default.
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• W2524276812 date "2016-08-08" @default.
• W2524276812 modified "2023-09-27" @default.
• W2524276812 title "Hepatotoxicity of Cassia fistula extracts in experimental chicks and assessment of clinical parameters" @default.
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