FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2524613228> ?p ?o ?g. }

• W2524613228 endingPage "135" @default.
• W2524613228 startingPage "130" @default.
• W2524613228 abstract "The release characteristics of lipophilic suppositories containing acetaminophen (AAP) were examined using four types of dissolution methods: the basket, paddle, dialysis tubing (DT) and flow-through cell (FTC) methods. The suitability of each apparatus for quality control in AAP compounded suppositories was evaluated using statistical procedures. More than 80% of the drug was released over 60 min in all the release methods studied, with the exception of the basket method. Reproducible and faster release was achieved using the paddle method at 100 and 200 rpm, whereas poor release occurred with the basket method. The mean dissolution time (MDT), maximum dissolved quantity of AAP at the end of the sampling time (Q) and dissolution efficiency (DE) were calculated by model-independent methods. The FTC method with a single chamber used in this study was also appreciable for AAP suppositories (Q of 100%, MDT of 71–91 min and DE of 75–80%). The DT apparatus is considered similar to the FTC apparatus from a quality control perspective for judging the release properties of lipophilic base suppositories containing AAP. However, even the single chamber FTC used in this study has potential as an in vitro drug release test for suppositories. The comparative dissolution method is expected to become one of the valuable tools for selecting an adequate dissolution test." @default.
• W2524613228 created "2016-10-07" @default.
• W2524613228 creator A5027485195 @default.
• W2524613228 creator A5043221287 @default.
• W2524613228 creator A5047722532 @default.
• W2524613228 creator A5069262657 @default.
• W2524613228 creator A5079478039 @default.
• W2524613228 creator A5085808615 @default.
• W2524613228 date "2016-09-30" @default.
• W2524613228 modified "2023-10-16" @default.
• W2524613228 title "Comparative release studies on suppositories using the basket, paddle, dialysis tubing and flow-through cell methods I. Acetaminophen in a lipophilic base suppository" @default.
• W2524613228 cites W1972058440 @default.
• W2524613228 cites W1983012462 @default.
• W2524613228 cites W1996253652 @default.
• W2524613228 cites W2002533466 @default.
• W2524613228 cites W2003345369 @default.
• W2524613228 cites W2007518524 @default.
• W2524613228 cites W2010869508 @default.
• W2524613228 cites W2021420859 @default.
• W2524613228 cites W2037324806 @default.
• W2524613228 cites W2053018604 @default.
• W2524613228 cites W2099607051 @default.
• W2524613228 cites W2103604760 @default.
• W2524613228 cites W2112281258 @default.
• W2524613228 cites W2115969113 @default.
• W2524613228 cites W2117457250 @default.
• W2524613228 cites W2147068483 @default.
• W2524613228 cites W2147620881 @default.
• W2524613228 cites W2162213916 @default.
• W2524613228 cites W2287800772 @default.
• W2524613228 cites W2321337839 @default.
• W2524613228 cites W2528896446 @default.
• W2524613228 cites W81728059 @default.
• W2524613228 doi "https://doi.org/10.1080/10837450.2016.1230132" @default.
• W2524613228 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27574857" @default.
• W2524613228 hasPublicationYear "2016" @default.
• W2524613228 type Work @default.
• W2524613228 sameAs 2524613228 @default.
• W2524613228 citedByCount "7" @default.
• W2524613228 countsByYear W25246132282017 @default.
• W2524613228 countsByYear W25246132282018 @default.
• W2524613228 countsByYear W25246132282019 @default.
• W2524613228 countsByYear W25246132282021 @default.
• W2524613228 countsByYear W25246132282022 @default.
• W2524613228 countsByYear W25246132282023 @default.
• W2524613228 crossrefType "journal-article" @default.
• W2524613228 hasAuthorship W2524613228A5027485195 @default.
• W2524613228 hasAuthorship W2524613228A5043221287 @default.
• W2524613228 hasAuthorship W2524613228A5047722532 @default.
• W2524613228 hasAuthorship W2524613228A5069262657 @default.
• W2524613228 hasAuthorship W2524613228A5079478039 @default.
• W2524613228 hasAuthorship W2524613228A5085808615 @default.
• W2524613228 hasConcept C121332964 @default.
• W2524613228 hasConcept C134519083 @default.
• W2524613228 hasConcept C14029885 @default.
• W2524613228 hasConcept C141071460 @default.
• W2524613228 hasConcept C147789679 @default.
• W2524613228 hasConcept C153294291 @default.
• W2524613228 hasConcept C159985019 @default.
• W2524613228 hasConcept C165150422 @default.
• W2524613228 hasConcept C185592680 @default.
• W2524613228 hasConcept C192562407 @default.
• W2524613228 hasConcept C199091049 @default.
• W2524613228 hasConcept C2778042862 @default.
• W2524613228 hasConcept C2779978075 @default.
• W2524613228 hasConcept C2781430271 @default.
• W2524613228 hasConcept C3019981671 @default.
• W2524613228 hasConcept C41625074 @default.
• W2524613228 hasConcept C43617362 @default.
• W2524613228 hasConcept C45904493 @default.
• W2524613228 hasConcept C55493867 @default.
• W2524613228 hasConcept C71924100 @default.
• W2524613228 hasConcept C77281830 @default.
• W2524613228 hasConcept C88380143 @default.
• W2524613228 hasConcept C98274493 @default.
• W2524613228 hasConceptScore W2524613228C121332964 @default.
• W2524613228 hasConceptScore W2524613228C134519083 @default.
• W2524613228 hasConceptScore W2524613228C14029885 @default.
• W2524613228 hasConceptScore W2524613228C141071460 @default.
• W2524613228 hasConceptScore W2524613228C147789679 @default.
• W2524613228 hasConceptScore W2524613228C153294291 @default.
• W2524613228 hasConceptScore W2524613228C159985019 @default.
• W2524613228 hasConceptScore W2524613228C165150422 @default.
• W2524613228 hasConceptScore W2524613228C185592680 @default.
• W2524613228 hasConceptScore W2524613228C192562407 @default.
• W2524613228 hasConceptScore W2524613228C199091049 @default.
• W2524613228 hasConceptScore W2524613228C2778042862 @default.
• W2524613228 hasConceptScore W2524613228C2779978075 @default.
• W2524613228 hasConceptScore W2524613228C2781430271 @default.
• W2524613228 hasConceptScore W2524613228C3019981671 @default.
• W2524613228 hasConceptScore W2524613228C41625074 @default.
• W2524613228 hasConceptScore W2524613228C43617362 @default.
• W2524613228 hasConceptScore W2524613228C45904493 @default.
• W2524613228 hasConceptScore W2524613228C55493867 @default.
• W2524613228 hasConceptScore W2524613228C71924100 @default.
• W2524613228 hasConceptScore W2524613228C77281830 @default.
• W2524613228 hasConceptScore W2524613228C88380143 @default.
• W2524613228 hasConceptScore W2524613228C98274493 @default.

• next