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- W2524661886 abstract "Orthostatic hypotension (OH) is a non-motor feature of Parkinson's disease (PD) that can have a significant impact on quality of life, particularly during various daily activities. Unfortunately the underlying mechanisms that are potentially contributing to OH in PD patients are not fully understood, but previous studies have indicated that the cardiovascular autonomic dysfunction is an important player. Recently, Nakamura et al. [ [1] Nakamura T. Hirayama M. Hara T. Mizutani Y. Suzuki J. Watanabe H. et al. Role of cardiac sympathetic nerves in preventing orthostatic hypotension in Parkinson's disease. Parkinsonism Relat. Disord. 2014; 20: 409-414 Abstract Full Text Full Text PDF PubMed Scopus (36) Google Scholar ] demonstrated that OH was clearly apparent in PD patients with a more severe loss of cardiac sympathetic innervation. However, no study has evaluated the sympathovagal balance in response to orthostatic stress in PD patients with and without OH. Thus, the present study was undertaken to test the hypothesis that PD patients with OH have impairment in cardiac autonomic modulation in response to active standing when compared to PD patients without OH and healthy subjects." @default.
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- W2524661886 date "2016-12-01" @default.
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- W2524661886 title "Symbolic dynamics of heart rate variability in Parkinson's disease patients with orthostatic hypotension" @default.
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- W2524661886 doi "https://doi.org/10.1016/j.ijcard.2016.09.091" @default.
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