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- W2525117635 abstract "ヌードマウスに移植したヒト悪性黒色腫(SK-14株)に対するrecombinantヒトTNF (rTNF: PT-050) の抗腫瘍効果を検討した。移植腫瘍の成長を確認後, 種々の濃度のrTNFを隔日6回静脈内あるいは腫瘍内に投与し, 投与終了後10日目に腫瘍増殖抑制効果を判定した。その結果, いずれの投与においても溶媒対照群と比較し腫瘍増殖抑制効果が観察された。また, 腫瘍部位の病理組織学的所見では出血像および腫瘍細胞の壊死像がいずれの投与法でも認められた。" @default.
- W2525117635 created "2016-10-07" @default.
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- W2525117635 date "1989-01-01" @default.
- W2525117635 modified "2023-09-25" @default.
- W2525117635 title "Antitumor effects of recombinant human TNF (PT-050) on nude mouse transplantable human malignant melanoma (SK-14 strain)." @default.
- W2525117635 cites W1542909857 @default.
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- W2525117635 doi "https://doi.org/10.5227/skincancer.4.388" @default.
- W2525117635 hasPublicationYear "1989" @default.
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