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• W2525272915 endingPage "2226" @default.
• W2525272915 startingPage "2217" @default.
• W2525272915 abstract "This paper presents a signal processing method for the electrophysiology simultaneously recorded during deep brain stimulation (DBS) as a research tool. Regarding the local field potential (LFP) signals recorded during stimulation, a novel method was proposed for removal of stimulation artifacts caused by the much stronger stimulating pulse compared to typical LFP. This artifact suppression method was tested and evaluated in an in vitro situation. The results indicate that the stimulation artifacts are well suppressed by this method. Secondly, this method was tested in vivo in Parkinson's disease (PD) patients. It was used to process the LFP signals recorded intraoperatively from PD patients to preliminarily explore the quantitative dependencies of beta band synchronization variations in the subthalamic nucleus (STNs) on the applied DBS parameters, including stimulation voltage, frequency and pulse width. The results confirm that DBS therapy can suppress excessive beta frequency activity and that the degree of attenuation increases with increasing DBS voltage within a range of 1-3 V and increasing DBS frequency within a range of 60-120 Hz. The proposed artifact suppression method provides technical support for exploring the direct effect of electrical stimulation on the brain activities." @default.
• W2525272915 created "2016-10-07" @default.
• W2525272915 creator A5022869475 @default.
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• W2525272915 date "2017-12-01" @default.
• W2525272915 modified "2023-10-15" @default.
• W2525272915 title "A Method for Removal of Deep Brain Stimulation Artifact From Local Field Potentials" @default.
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• W2525272915 doi "https://doi.org/10.1109/tnsre.2016.2613412" @default.
• W2525272915 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28113981" @default.
• W2525272915 hasPublicationYear "2017" @default.
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