Matches in SemOpenAlex for { <https://semopenalex.org/work/W2525711035> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2525711035 endingPage "218" @default.
- W2525711035 startingPage "213" @default.
- W2525711035 abstract "Patients affected with AIDS develop a wide range of cutaneous neoplastic and nonneoplastic disorders. However, it is not clear whether pathological skin changes, observed in HIV-1 seropositive subjects during the course of disease are correlated to HIV-1 infection. To verify the effect of HIV-1 on human epidermal keratinocytes (HEKs), we performed virological and ultrastructural (transmission and scanning electron microscopy - TEM, SEM) studies. For this purpose cultured HEKs were studied following incubation with cell-free HIV-1 or HIV-1/infected cells, treatment with recombinant gp120 and treatment with Tat protein. PCR analysis performed on cell-free, virus-treated HEKs, constantly demonstrated negative results. Ultrastructural observations showed cytotoxic, stress-induced HEK changes, including : 1. cell vacuolization ; 2. disordered cytoskeletal arrangement ; 3. junctional leakage ; 4. surface blebbing. Our results suggest that, although HEKs appear resistant to HIV-I infection in our experimental setting, they undergo a cascade of stress-induced subcellular events which possibly impair their in vivo physiological functions." @default.
- W2525711035 created "2016-10-07" @default.
- W2525711035 creator A5017176042 @default.
- W2525711035 creator A5020075089 @default.
- W2525711035 creator A5024760076 @default.
- W2525711035 creator A5030021056 @default.
- W2525711035 creator A5036347819 @default.
- W2525711035 creator A5055536871 @default.
- W2525711035 creator A5067085999 @default.
- W2525711035 creator A5067870640 @default.
- W2525711035 creator A5077801788 @default.
- W2525711035 date "1996-01-01" @default.
- W2525711035 modified "2023-09-23" @default.
- W2525711035 title "Early ultrastructural changes of human keratinocytes after HIV-1 contact : an in vitro study" @default.
- W2525711035 hasPublicationYear "1996" @default.
- W2525711035 type Work @default.
- W2525711035 sameAs 2525711035 @default.
- W2525711035 citedByCount "1" @default.
- W2525711035 countsByYear W25257110352014 @default.
- W2525711035 crossrefType "journal-article" @default.
- W2525711035 hasAuthorship W2525711035A5017176042 @default.
- W2525711035 hasAuthorship W2525711035A5020075089 @default.
- W2525711035 hasAuthorship W2525711035A5024760076 @default.
- W2525711035 hasAuthorship W2525711035A5030021056 @default.
- W2525711035 hasAuthorship W2525711035A5036347819 @default.
- W2525711035 hasAuthorship W2525711035A5055536871 @default.
- W2525711035 hasAuthorship W2525711035A5067085999 @default.
- W2525711035 hasAuthorship W2525711035A5067870640 @default.
- W2525711035 hasAuthorship W2525711035A5077801788 @default.
- W2525711035 hasConcept C142669718 @default.
- W2525711035 hasConcept C142724271 @default.
- W2525711035 hasConcept C1491633281 @default.
- W2525711035 hasConcept C150903083 @default.
- W2525711035 hasConcept C154317977 @default.
- W2525711035 hasConcept C159047783 @default.
- W2525711035 hasConcept C202751555 @default.
- W2525711035 hasConcept C203014093 @default.
- W2525711035 hasConcept C207001950 @default.
- W2525711035 hasConcept C2522874641 @default.
- W2525711035 hasConcept C2778614373 @default.
- W2525711035 hasConcept C54355233 @default.
- W2525711035 hasConcept C55493867 @default.
- W2525711035 hasConcept C71924100 @default.
- W2525711035 hasConcept C86803240 @default.
- W2525711035 hasConcept C87555872 @default.
- W2525711035 hasConceptScore W2525711035C142669718 @default.
- W2525711035 hasConceptScore W2525711035C142724271 @default.
- W2525711035 hasConceptScore W2525711035C1491633281 @default.
- W2525711035 hasConceptScore W2525711035C150903083 @default.
- W2525711035 hasConceptScore W2525711035C154317977 @default.
- W2525711035 hasConceptScore W2525711035C159047783 @default.
- W2525711035 hasConceptScore W2525711035C202751555 @default.
- W2525711035 hasConceptScore W2525711035C203014093 @default.
- W2525711035 hasConceptScore W2525711035C207001950 @default.
- W2525711035 hasConceptScore W2525711035C2522874641 @default.
- W2525711035 hasConceptScore W2525711035C2778614373 @default.
- W2525711035 hasConceptScore W2525711035C54355233 @default.
- W2525711035 hasConceptScore W2525711035C55493867 @default.
- W2525711035 hasConceptScore W2525711035C71924100 @default.
- W2525711035 hasConceptScore W2525711035C86803240 @default.
- W2525711035 hasConceptScore W2525711035C87555872 @default.
- W2525711035 hasIssue "3" @default.
- W2525711035 hasLocation W25257110351 @default.
- W2525711035 hasOpenAccess W2525711035 @default.
- W2525711035 hasPrimaryLocation W25257110351 @default.
- W2525711035 hasRelatedWork W1593845441 @default.
- W2525711035 hasRelatedWork W179303711 @default.
- W2525711035 hasRelatedWork W1890189475 @default.
- W2525711035 hasRelatedWork W1978604397 @default.
- W2525711035 hasRelatedWork W1982201893 @default.
- W2525711035 hasRelatedWork W2025312536 @default.
- W2525711035 hasRelatedWork W2032891625 @default.
- W2525711035 hasRelatedWork W2042343908 @default.
- W2525711035 hasRelatedWork W2050303117 @default.
- W2525711035 hasRelatedWork W2055634153 @default.
- W2525711035 hasRelatedWork W2056779555 @default.
- W2525711035 hasRelatedWork W2063203244 @default.
- W2525711035 hasRelatedWork W2066167279 @default.
- W2525711035 hasRelatedWork W2068108255 @default.
- W2525711035 hasRelatedWork W2079748356 @default.
- W2525711035 hasRelatedWork W2099864019 @default.
- W2525711035 hasRelatedWork W2196437126 @default.
- W2525711035 hasRelatedWork W31295220 @default.
- W2525711035 hasRelatedWork W1805014846 @default.
- W2525711035 hasRelatedWork W2429622810 @default.
- W2525711035 hasVolume "6" @default.
- W2525711035 isParatext "false" @default.
- W2525711035 isRetracted "false" @default.
- W2525711035 magId "2525711035" @default.
- W2525711035 workType "article" @default.