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- W2525711237 abstract "Cell-to-cell signals of the diffusible signal factor (DSF) family are cis-2-unsaturated fatty acids of differing chain length and branching pattern. DSF signalling has been described in diverse bacteria to include plant and human pathogens where it acts to regulate functions such as biofilm formation, antibiotic tolerance and the production of virulence factors. DSF family signals can also participate in interspecies signalling with other bacteria and interkingdom signalling such as with the yeast Candida albicans. Interference with DSF signalling may afford new opportunities for the control of bacterial disease. Such strategies will depend in part on detailed knowledge of the molecular mechanisms underlying the processes of signal synthesis, perception and turnover. Here, I review both recent progress in understanding DSF signalling at the molecular level and prospects for translating this knowledge into approaches for disease control." @default.
- W2525711237 created "2016-10-07" @default.
- W2525711237 creator A5019993942 @default.
- W2525711237 date "2016-11-10" @default.
- W2525711237 modified "2023-10-15" @default.
- W2525711237 title "Diffusible signal factor-dependent quorum sensing in pathogenic bacteria and its exploitation for disease control" @default.
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- W2525711237 doi "https://doi.org/10.1111/jam.13307" @default.
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