FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2525822080> ?p ?o ?g. }

• W2525822080 endingPage "310" @default.
• W2525822080 startingPage "302" @default.
• W2525822080 abstract "<b><i>Objective:</i></b> To assess the immunosuppressive effect of R-CHOP in patients with B-cell lymphoma at 2 years. <b><i>Methods:</i></b> Parameters of humoral and cell-mediated immunity were assessed in 89 patients with diffuse large B-cell lymphoma or follicular lymphoma before and after 6-8 cycles of R-CHOP-14 or R-CHOP-21 regimen. <b><i>Results:</i></b> Data on pre- and posttreatment serum IgG (sIgG) levels were available for all 89 patients, while the corresponding data on serum CD20+, CD3+, CD4+, and CD8+ lymphocyte counts were available in only 43. Median sIgG levels significantly decreased from 1,221 mg/dl (baseline) to 733 mg/dl (after chemotherapy) (p < 0.001). Although CD20+ and CD4+ cell counts decreased (p < 0.001), no significant effect of chemotherapy on CD3+ and CD8+ cell counts was observed. CD20+ cell counts were restored to baseline levels at the 12-month follow-up. sIgG levels and CD4+ cell counts were not completely restored at 24 months, indicating a sustained immunosuppressive effect of R-CHOP in these patients. The incidence of infections over the 2-year period was 16.3-23.6%. <b><i>Conclusion:</i></b> The immunosuppressive effect of R-CHOP in newly diagnosed cases of B-cell lymphoma tends to persist for >2 years, although sIgG levels were restored more quickly than CD4+ cell counts." @default.
• W2525822080 created "2016-10-07" @default.
• W2525822080 creator A5002528518 @default.
• W2525822080 creator A5013870945 @default.
• W2525822080 creator A5015841809 @default.
• W2525822080 creator A5023452181 @default.
• W2525822080 creator A5025486438 @default.
• W2525822080 creator A5029952836 @default.
• W2525822080 creator A5038103231 @default.
• W2525822080 creator A5051705924 @default.
• W2525822080 creator A5061237838 @default.
• W2525822080 creator A5061871076 @default.
• W2525822080 creator A5078730361 @default.
• W2525822080 creator A5087299748 @default.
• W2525822080 date "2016-01-01" @default.
• W2525822080 modified "2023-09-25" @default.
• W2525822080 title "Influence of R-CHOP Therapy on Immune System Restoration in Patients with B-Cell Lymphoma" @default.
• W2525822080 cites W1915689252 @default.
• W2525822080 cites W1965723348 @default.
• W2525822080 cites W1974369659 @default.
• W2525822080 cites W2013176883 @default.
• W2525822080 cites W2017866273 @default.
• W2525822080 cites W2028375716 @default.
• W2525822080 cites W2030373021 @default.
• W2525822080 cites W2058015212 @default.
• W2525822080 cites W2063792914 @default.
• W2525822080 cites W2070412267 @default.
• W2525822080 cites W2070795385 @default.
• W2525822080 cites W2101141816 @default.
• W2525822080 cites W2101648653 @default.
• W2525822080 cites W2101939391 @default.
• W2525822080 cites W2104413012 @default.
• W2525822080 cites W2104940816 @default.
• W2525822080 cites W2116052020 @default.
• W2525822080 cites W2123439935 @default.
• W2525822080 cites W2130093747 @default.
• W2525822080 cites W2138404218 @default.
• W2525822080 cites W2140888629 @default.
• W2525822080 cites W2152107828 @default.
• W2525822080 cites W2154643481 @default.
• W2525822080 cites W2160305510 @default.
• W2525822080 cites W2206199245 @default.
• W2525822080 cites W2402735797 @default.
• W2525822080 doi "https://doi.org/10.1159/000449251" @default.
• W2525822080 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5467439" @default.
• W2525822080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27682623" @default.
• W2525822080 hasPublicationYear "2016" @default.
• W2525822080 type Work @default.
• W2525822080 sameAs 2525822080 @default.
• W2525822080 citedByCount "12" @default.
• W2525822080 countsByYear W25258220802017 @default.
• W2525822080 countsByYear W25258220802018 @default.
• W2525822080 countsByYear W25258220802019 @default.
• W2525822080 countsByYear W25258220802020 @default.
• W2525822080 countsByYear W25258220802021 @default.
• W2525822080 countsByYear W25258220802022 @default.
• W2525822080 countsByYear W25258220802023 @default.
• W2525822080 crossrefType "journal-article" @default.
• W2525822080 hasAuthorship W2525822080A5002528518 @default.
• W2525822080 hasAuthorship W2525822080A5013870945 @default.
• W2525822080 hasAuthorship W2525822080A5015841809 @default.
• W2525822080 hasAuthorship W2525822080A5023452181 @default.
• W2525822080 hasAuthorship W2525822080A5025486438 @default.
• W2525822080 hasAuthorship W2525822080A5029952836 @default.
• W2525822080 hasAuthorship W2525822080A5038103231 @default.
• W2525822080 hasAuthorship W2525822080A5051705924 @default.
• W2525822080 hasAuthorship W2525822080A5061237838 @default.
• W2525822080 hasAuthorship W2525822080A5061871076 @default.
• W2525822080 hasAuthorship W2525822080A5078730361 @default.
• W2525822080 hasAuthorship W2525822080A5087299748 @default.
• W2525822080 hasBestOaLocation W25258220801 @default.
• W2525822080 hasConcept C126322002 @default.
• W2525822080 hasConcept C159654299 @default.
• W2525822080 hasConcept C167672396 @default.
• W2525822080 hasConcept C18031839 @default.
• W2525822080 hasConcept C203014093 @default.
• W2525822080 hasConcept C2776694085 @default.
• W2525822080 hasConcept C2777058707 @default.
• W2525822080 hasConcept C2777257650 @default.
• W2525822080 hasConcept C2778453870 @default.
• W2525822080 hasConcept C2778559949 @default.
• W2525822080 hasConcept C2779338263 @default.
• W2525822080 hasConcept C2779725641 @default.
• W2525822080 hasConcept C71924100 @default.
• W2525822080 hasConcept C8891405 @default.
• W2525822080 hasConcept C90924648 @default.
• W2525822080 hasConceptScore W2525822080C126322002 @default.
• W2525822080 hasConceptScore W2525822080C159654299 @default.
• W2525822080 hasConceptScore W2525822080C167672396 @default.
• W2525822080 hasConceptScore W2525822080C18031839 @default.
• W2525822080 hasConceptScore W2525822080C203014093 @default.
• W2525822080 hasConceptScore W2525822080C2776694085 @default.
• W2525822080 hasConceptScore W2525822080C2777058707 @default.
• W2525822080 hasConceptScore W2525822080C2777257650 @default.
• W2525822080 hasConceptScore W2525822080C2778453870 @default.
• W2525822080 hasConceptScore W2525822080C2778559949 @default.
• W2525822080 hasConceptScore W2525822080C2779338263 @default.
• W2525822080 hasConceptScore W2525822080C2779725641 @default.

• next