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• W2526322416 abstract "Non-covalent complexes (NCC) between hexose monophosphates (HexP) and arginine (R) were analyzed using ESI MS and MS/MS in negative mode under different (hard, HC and soft, SC) desolvation conditions. High resolution mass spectrometry (HRMS) revealed the presence of different ionic species, namely, homo- and heteromultimers of R and HexP. Deprotonated heterodimers and corresponding sodiated species were enhanced under HC likely due to a decrease in available charge number associated with the reduction of H+/Na+ exchange. The quantum calculations showed that the formation of covalent systems is very little exothermic, therefore, such systems are disfavored. Desolvation dependent CID spectra of deprotonated [(HexP+R)‒H]- complexes demonstrated that they can exist within the hydrogen bond (HB) and salt bridge (SB) forms, yielding either NCC separation or covalent bond cleavages, respectively. Although HB forms are the main species, they cannot survive under HC; therefore, the minor SB forms became detectable. Energy-resolved mass spectrometry (ERMS) experiments revealed diagnostic fragment ions from both SB and HB forms, providing evidence that these isomeric forms are inconvertible. SB formation should result from the ionic interactions of highly acidic group of HexP with strongly basic guanidine group of arginine and thus requires an arginine zwitterion (ZW) form. This was confirmed by quantum calculations. Ion-ion interactions are significantly affected by the presence of sodium cation as demonstrated by the fragmentation patterns of sodiated complex species. Regarding CID data, only SB between protonated amino group of R and deprotonated phosphate group of HexP could be suggested, but the primary amine is not enough basic then, the SB must be fleeting. Nevertheless, the observation of the covalent bond cleavages suggests the presence of structures with a free negative charge able to induce fragmentations. Indeed, according to quantum calculations, solvated salt (SS) systems involving Na+/COO- salt solvated by neutral phosphate and negative charge on sugar ring are preferentially formed." @default.
• W2526322416 created "2016-10-07" @default.
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• W2526322416 date "2017-03-01" @default.
• W2526322416 modified "2023-10-13" @default.
• W2526322416 title "Meaning and consequence of the coexistence of competitive hydrogen bond/salt forms on the dissociation orientation of non-covalent complexes" @default.
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• W2526322416 cites W1971970279 @default.
• W2526322416 cites W1980702512 @default.
• W2526322416 cites W1984257456 @default.
• W2526322416 cites W1986256685 @default.
• W2526322416 cites W1988105445 @default.
• W2526322416 cites W1991106648 @default.
• W2526322416 cites W1998342925 @default.
• W2526322416 cites W1998862337 @default.
• W2526322416 cites W1999365897 @default.
• W2526322416 cites W2000125682 @default.
• W2526322416 cites W2000518567 @default.
• W2526322416 cites W2000574754 @default.
• W2526322416 cites W2002433816 @default.
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• W2526322416 cites W2006496491 @default.
• W2526322416 cites W2010026236 @default.
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• W2526322416 cites W2017926405 @default.
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• W2526322416 cites W2021230992 @default.
• W2526322416 cites W2024487566 @default.
• W2526322416 cites W2026750756 @default.
• W2526322416 cites W2033711082 @default.
• W2526322416 cites W2036032674 @default.
• W2526322416 cites W2039663664 @default.
• W2526322416 cites W2040074208 @default.
• W2526322416 cites W2041844393 @default.
• W2526322416 cites W2044039308 @default.
• W2526322416 cites W2045852175 @default.
• W2526322416 cites W2050452700 @default.
• W2526322416 cites W2051001572 @default.
• W2526322416 cites W2052195975 @default.
• W2526322416 cites W2056703835 @default.
• W2526322416 cites W2058319565 @default.
• W2526322416 cites W2062616085 @default.
• W2526322416 cites W2067809671 @default.
• W2526322416 cites W2074616266 @default.
• W2526322416 cites W2078531661 @default.
• W2526322416 cites W2080354700 @default.
• W2526322416 cites W2082781271 @default.
• W2526322416 cites W2084173425 @default.
• W2526322416 cites W2084528818 @default.
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• W2526322416 doi "https://doi.org/10.1016/j.jchromb.2016.09.038" @default.
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• W2526322416 hasPublicationYear "2017" @default.
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