Matches in SemOpenAlex for { <https://semopenalex.org/work/W2526698736> ?p ?o ?g. }
- W2526698736 abstract "Colorectal cancer (CRC) is one of the most malignant tumors in both sexesamong all types of tumors worldwide. Up to now, no precise biomarker has beencapable of accurately predicting the prognosis for patients with CRC.Therefore, it is essential for us to find a new biomarker to predict theprognosis, overall survival, and disease-free survival of patients with CRC,especially for those patients who have a distant metastasis. There is a growingconcern over the issues that osteopontin (OPN), a multifunction phosphorylatedprotein, has been identified in recent years among multiple tumors types,including CRC. There is increasing evidence showing that high expression of OPNis related to the proliferation, invasion and metastasis of CRC. OPN could supportmalignant formation by inducing tumor angiogenesis; aggravating the degradationof extracellular matrix; promoting chemo taxis,adhesion, and metastasis of tumors and affecting tumor immunity and apoptosisbased on various complex mechanisms. More intensive studies are required in thefuture to clarify the roles of OPN and its related genes, relevant receptors,protein structure, biological features, and complex molecular mechanisms incolorectal carcinogenesis, as well as to develop beneficial agents for theclinical treatment of CRC to improve patient prognosis." @default.
- W2526698736 created "2016-10-07" @default.
- W2526698736 creator A5019891778 @default.
- W2526698736 creator A5023095500 @default.
- W2526698736 creator A5026111824 @default.
- W2526698736 creator A5044761368 @default.
- W2526698736 date "2016-01-01" @default.
- W2526698736 modified "2023-09-26" @default.
- W2526698736 title "Role of Osteopontin in the Carcinogenesis and Metastasis of Colorectal Cancer" @default.
- W2526698736 cites W1082536769 @default.
- W2526698736 cites W1417661680 @default.
- W2526698736 cites W1515959446 @default.
- W2526698736 cites W1530444778 @default.
- W2526698736 cites W1603224517 @default.
- W2526698736 cites W1629767962 @default.
- W2526698736 cites W1670890407 @default.
- W2526698736 cites W1757407923 @default.
- W2526698736 cites W1758762952 @default.
- W2526698736 cites W1967446368 @default.
- W2526698736 cites W1972959987 @default.
- W2526698736 cites W1983567075 @default.
- W2526698736 cites W1985670835 @default.
- W2526698736 cites W1999157060 @default.
- W2526698736 cites W2001165015 @default.
- W2526698736 cites W2003721635 @default.
- W2526698736 cites W2016514520 @default.
- W2526698736 cites W2017604980 @default.
- W2526698736 cites W2022905622 @default.
- W2526698736 cites W2025474825 @default.
- W2526698736 cites W2032057318 @default.
- W2526698736 cites W2047136859 @default.
- W2526698736 cites W2050531469 @default.
- W2526698736 cites W2051626617 @default.
- W2526698736 cites W2053101826 @default.
- W2526698736 cites W2077981972 @default.
- W2526698736 cites W2093827445 @default.
- W2526698736 cites W2097489402 @default.
- W2526698736 cites W2105182937 @default.
- W2526698736 cites W2114338519 @default.
- W2526698736 cites W2120091640 @default.
- W2526698736 cites W2121532120 @default.
- W2526698736 cites W2136878446 @default.
- W2526698736 cites W2140484012 @default.
- W2526698736 cites W2143527813 @default.
- W2526698736 cites W2158194704 @default.
- W2526698736 cites W2166811751 @default.
- W2526698736 cites W2168855182 @default.
- W2526698736 cites W2187985754 @default.
- W2526698736 cites W2197912162 @default.
- W2526698736 cites W2209093312 @default.
- W2526698736 cites W2211602021 @default.
- W2526698736 cites W2213867049 @default.
- W2526698736 cites W2262238062 @default.
- W2526698736 cites W2273053488 @default.
- W2526698736 cites W2280085711 @default.
- W2526698736 cites W2293485767 @default.
- W2526698736 cites W2298127602 @default.
- W2526698736 cites W2299968420 @default.
- W2526698736 cites W2308033649 @default.
- W2526698736 cites W2318349725 @default.
- W2526698736 cites W2324999500 @default.
- W2526698736 cites W2396889707 @default.
- W2526698736 cites W2443425808 @default.
- W2526698736 cites W420887566 @default.
- W2526698736 cites W617460480 @default.
- W2526698736 cites W838262002 @default.
- W2526698736 cites W2438892792 @default.
- W2526698736 doi "https://doi.org/10.4236/jct.2016.710074" @default.
- W2526698736 hasPublicationYear "2016" @default.
- W2526698736 type Work @default.
- W2526698736 sameAs 2526698736 @default.
- W2526698736 citedByCount "3" @default.
- W2526698736 countsByYear W25266987362018 @default.
- W2526698736 countsByYear W25266987362019 @default.
- W2526698736 crossrefType "journal-article" @default.
- W2526698736 hasAuthorship W2526698736A5019891778 @default.
- W2526698736 hasAuthorship W2526698736A5023095500 @default.
- W2526698736 hasAuthorship W2526698736A5026111824 @default.
- W2526698736 hasAuthorship W2526698736A5044761368 @default.
- W2526698736 hasBestOaLocation W25266987361 @default.
- W2526698736 hasConcept C121608353 @default.
- W2526698736 hasConcept C126322002 @default.
- W2526698736 hasConcept C143998085 @default.
- W2526698736 hasConcept C189165786 @default.
- W2526698736 hasConcept C2779013556 @default.
- W2526698736 hasConcept C2780394083 @default.
- W2526698736 hasConcept C2780804394 @default.
- W2526698736 hasConcept C2781197716 @default.
- W2526698736 hasConcept C502942594 @default.
- W2526698736 hasConcept C526805850 @default.
- W2526698736 hasConcept C55493867 @default.
- W2526698736 hasConcept C555283112 @default.
- W2526698736 hasConcept C71924100 @default.
- W2526698736 hasConcept C86803240 @default.
- W2526698736 hasConcept C95444343 @default.
- W2526698736 hasConceptScore W2526698736C121608353 @default.
- W2526698736 hasConceptScore W2526698736C126322002 @default.
- W2526698736 hasConceptScore W2526698736C143998085 @default.
- W2526698736 hasConceptScore W2526698736C189165786 @default.
- W2526698736 hasConceptScore W2526698736C2779013556 @default.