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- W2526854172 endingPage "370" @default.
- W2526854172 startingPage "337" @default.
- W2526854172 abstract "Transcriptomics, the high-throughput characterization of RNAs, has been instrumental in defining pathogenic signatures in human autoimmunity and autoinflammation. It enabled the identification of new therapeutic targets in IFN-, IL-1- and IL-17-mediated diseases. Applied to immunomonitoring, transcriptomics is starting to unravel diagnostic and prognostic signatures that stratify patients, track molecular changes associated with disease activity, define personalized treatment strategies, and generally inform clinical practice. Herein, we review the use of transcriptomics to define mechanistic, diagnostic, and predictive signatures in human autoimmunity and autoinflammation. We discuss some of the analytical approaches applied to extract biological knowledge from high-dimensional data sets. Finally, we touch upon emerging applications of transcriptomics to study eQTLs, B and T cell repertoire diversity, and isoform usage." @default.
- W2526854172 created "2016-10-07" @default.
- W2526854172 creator A5002962815 @default.
- W2526854172 creator A5036286228 @default.
- W2526854172 creator A5041412546 @default.
- W2526854172 creator A5049692454 @default.
- W2526854172 date "2017-04-26" @default.
- W2526854172 modified "2023-10-18" @default.
- W2526854172 title "Understanding Human Autoimmunity and Autoinflammation Through Transcriptomics" @default.
- W2526854172 cites W1492996609 @default.
- W2526854172 cites W1498105805 @default.
- W2526854172 cites W1516874144 @default.
- W2526854172 cites W1519521580 @default.
- W2526854172 cites W1522974510 @default.
- W2526854172 cites W1542158376 @default.
- W2526854172 cites W1544174173 @default.
- W2526854172 cites W1580018887 @default.
- W2526854172 cites W1593743891 @default.
- W2526854172 cites W1601709990 @default.
- W2526854172 cites W1652582743 @default.
- W2526854172 cites W1679569810 @default.
- W2526854172 cites W1770946500 @default.
- W2526854172 cites W1779387069 @default.
- W2526854172 cites W1827062277 @default.
- W2526854172 cites W1852489937 @default.
- W2526854172 cites W1885840961 @default.
- W2526854172 cites W1900316083 @default.
- W2526854172 cites W1902375722 @default.
- W2526854172 cites W1936939552 @default.
- W2526854172 cites W1964372737 @default.
- W2526854172 cites W1965672602 @default.
- W2526854172 cites W1967139098 @default.
- W2526854172 cites W1968178474 @default.
- W2526854172 cites W1968295744 @default.
- W2526854172 cites W1968701038 @default.
- W2526854172 cites W1969218538 @default.
- W2526854172 cites W1973354423 @default.
- W2526854172 cites W1978503782 @default.
- W2526854172 cites W1980842187 @default.
- W2526854172 cites W1982230962 @default.
- W2526854172 cites W1983378819 @default.
- W2526854172 cites W1985702891 @default.
- W2526854172 cites W1986829091 @default.
- W2526854172 cites W1987971789 @default.
- W2526854172 cites W1988458651 @default.
- W2526854172 cites W1989590412 @default.
- W2526854172 cites W1989885720 @default.
- W2526854172 cites W1992300913 @default.
- W2526854172 cites W1992373415 @default.
- W2526854172 cites W1993616000 @default.
- W2526854172 cites W1993928780 @default.
- W2526854172 cites W1994179040 @default.
- W2526854172 cites W1994488319 @default.
- W2526854172 cites W1995106708 @default.
- W2526854172 cites W1997163824 @default.
- W2526854172 cites W1999901184 @default.
- W2526854172 cites W2000177767 @default.
- W2526854172 cites W2000934898 @default.
- W2526854172 cites W2001607419 @default.
- W2526854172 cites W2003425690 @default.
- W2526854172 cites W2006353424 @default.
- W2526854172 cites W2006399653 @default.
- W2526854172 cites W2010789111 @default.
- W2526854172 cites W2012077729 @default.
- W2526854172 cites W2015008025 @default.
- W2526854172 cites W2015310325 @default.
- W2526854172 cites W2016073955 @default.
- W2526854172 cites W2016103707 @default.
- W2526854172 cites W2016447788 @default.
- W2526854172 cites W2017213437 @default.
- W2526854172 cites W2018071669 @default.
- W2526854172 cites W2021271171 @default.
- W2526854172 cites W2022316530 @default.
- W2526854172 cites W2023709564 @default.
- W2526854172 cites W2024192805 @default.
- W2526854172 cites W2024679195 @default.
- W2526854172 cites W2025056438 @default.
- W2526854172 cites W2028236537 @default.
- W2526854172 cites W2028368428 @default.
- W2526854172 cites W2031097604 @default.
- W2526854172 cites W2033903988 @default.
- W2526854172 cites W2034583127 @default.
- W2526854172 cites W2035451872 @default.
- W2526854172 cites W2036095604 @default.
- W2526854172 cites W2037665605 @default.
- W2526854172 cites W2040733258 @default.
- W2526854172 cites W2041467022 @default.
- W2526854172 cites W2043287930 @default.
- W2526854172 cites W2044493383 @default.
- W2526854172 cites W2044702943 @default.
- W2526854172 cites W2045189254 @default.
- W2526854172 cites W2046330020 @default.
- W2526854172 cites W2046530746 @default.
- W2526854172 cites W2048120844 @default.
- W2526854172 cites W2049220563 @default.
- W2526854172 cites W2049820652 @default.
- W2526854172 cites W2049858255 @default.
- W2526854172 cites W2051604556 @default.