FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2527157411> ?p ?o ?g. }

• W2527157411 endingPage "10205" @default.
• W2527157411 startingPage "10199" @default.
• W2527157411 abstract "To enhance the sensitivity and selectivity of surface-based (bio)sensors, it is of crucial importance to diminish background signals that arise from the nonspecific binding of biomolecules, so-called biofouling. Zwitterionic polymer brushes have been shown to be excellent antifouling materials. However, for sensing purposes, antifouling does not suffice but needs to be combined with the possibility to efficiently modify the brush with recognition units. So far this has been achieved only at the expense of either antifouling properties or binding capacity. Herein we present a conceptually new approach by integrating both characteristics into a single tailor-made monomer: a novel sulfobetaine-based zwitterionic monomer equipped with a clickable azide moiety. Copolymerization of this monomer with a well-established standard sulfobetaine monomer results in highly antifouling surface coatings with a large yet tunable number of clickable groups present throughout the entire brush. Subsequent functionalization of the azido brushes via widely used strain-promoted alkyne azide click reactions yields fully zwitterionic 3D-functionalized coatings with a recognition unit of choice that can be tailored for any specific application. Here we show a proof of principle with biotin-functionalized brushes on Si3N4 that combine excellent antifouling properties with specific avidin binding from a protein mixture. The signal-to-noise ratio is significantly improved over that of traditional chain-end modification of sulfobetaine polymer brushes, even if the azide content is lowered to 1%. This therefore offers a viable approach to the development of biosensors with greatly enhanced performance on any surface." @default.
• W2527157411 created "2016-10-07" @default.
• W2527157411 creator A5002643806 @default.
• W2527157411 creator A5042575790 @default.
• W2527157411 creator A5055120115 @default.
• W2527157411 creator A5087287749 @default.
• W2527157411 date "2016-09-30" @default.
• W2527157411 modified "2023-10-12" @default.
• W2527157411 title "Efficient and Tunable Three-Dimensional Functionalization of Fully Zwitterionic Antifouling Surface Coatings" @default.
• W2527157411 cites W1614924343 @default.
• W2527157411 cites W1906750864 @default.
• W2527157411 cites W1965006117 @default.
• W2527157411 cites W1966006560 @default.
• W2527157411 cites W1966526850 @default.
• W2527157411 cites W1973634364 @default.
• W2527157411 cites W1992090149 @default.
• W2527157411 cites W1992265371 @default.
• W2527157411 cites W1995829317 @default.
• W2527157411 cites W2008303284 @default.
• W2527157411 cites W2023706718 @default.
• W2527157411 cites W2025201514 @default.
• W2527157411 cites W2031599845 @default.
• W2527157411 cites W2034520377 @default.
• W2527157411 cites W2034529942 @default.
• W2527157411 cites W2034608688 @default.
• W2527157411 cites W2043397035 @default.
• W2527157411 cites W2047729683 @default.
• W2527157411 cites W2054867301 @default.
• W2527157411 cites W2057870441 @default.
• W2527157411 cites W2062489038 @default.
• W2527157411 cites W2062535319 @default.
• W2527157411 cites W2075423460 @default.
• W2527157411 cites W2083932432 @default.
• W2527157411 cites W2084470903 @default.
• W2527157411 cites W2084630129 @default.
• W2527157411 cites W2085977870 @default.
• W2527157411 cites W2090568310 @default.
• W2527157411 cites W2091442580 @default.
• W2527157411 cites W2097034060 @default.
• W2527157411 cites W2119961090 @default.
• W2527157411 cites W2124973460 @default.
• W2527157411 cites W2134823402 @default.
• W2527157411 cites W2154239612 @default.
• W2527157411 cites W2171838360 @default.
• W2527157411 cites W2287832430 @default.
• W2527157411 cites W2291098060 @default.
• W2527157411 cites W2316287488 @default.
• W2527157411 cites W2318631380 @default.
• W2527157411 cites W2320083771 @default.
• W2527157411 cites W2324177153 @default.
• W2527157411 cites W2332979239 @default.
• W2527157411 doi "https://doi.org/10.1021/acs.langmuir.6b02622" @default.
• W2527157411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27687696" @default.
• W2527157411 hasPublicationYear "2016" @default.
• W2527157411 type Work @default.
• W2527157411 sameAs 2527157411 @default.
• W2527157411 citedByCount "57" @default.
• W2527157411 countsByYear W25271574112017 @default.
• W2527157411 countsByYear W25271574112018 @default.
• W2527157411 countsByYear W25271574112019 @default.
• W2527157411 countsByYear W25271574112020 @default.
• W2527157411 countsByYear W25271574112021 @default.
• W2527157411 countsByYear W25271574112022 @default.
• W2527157411 countsByYear W25271574112023 @default.
• W2527157411 crossrefType "journal-article" @default.
• W2527157411 hasAuthorship W2527157411A5002643806 @default.
• W2527157411 hasAuthorship W2527157411A5042575790 @default.
• W2527157411 hasAuthorship W2527157411A5055120115 @default.
• W2527157411 hasAuthorship W2527157411A5087287749 @default.
• W2527157411 hasBestOaLocation W25271574111 @default.
• W2527157411 hasConcept C115537861 @default.
• W2527157411 hasConcept C118792377 @default.
• W2527157411 hasConcept C147789679 @default.
• W2527157411 hasConcept C15920480 @default.
• W2527157411 hasConcept C160756335 @default.
• W2527157411 hasConcept C161790260 @default.
• W2527157411 hasConcept C166940927 @default.
• W2527157411 hasConcept C171250308 @default.
• W2527157411 hasConcept C176406525 @default.
• W2527157411 hasConcept C178790620 @default.
• W2527157411 hasConcept C185592680 @default.
• W2527157411 hasConcept C188027245 @default.
• W2527157411 hasConcept C192562407 @default.
• W2527157411 hasConcept C21951064 @default.
• W2527157411 hasConcept C2776568683 @default.
• W2527157411 hasConcept C2778204606 @default.
• W2527157411 hasConcept C2780997848 @default.
• W2527157411 hasConcept C2781018886 @default.
• W2527157411 hasConcept C41625074 @default.
• W2527157411 hasConcept C44228677 @default.
• W2527157411 hasConcept C49853544 @default.
• W2527157411 hasConcept C521977710 @default.
• W2527157411 hasConcept C55493867 @default.
• W2527157411 hasConcept C6047279 @default.
• W2527157411 hasConceptScore W2527157411C115537861 @default.
• W2527157411 hasConceptScore W2527157411C118792377 @default.
• W2527157411 hasConceptScore W2527157411C147789679 @default.
• W2527157411 hasConceptScore W2527157411C15920480 @default.

• next