FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2527303319> ?p ?o ?g. }

• W2527303319 endingPage "508" @default.
• W2527303319 startingPage "487" @default.
• W2527303319 abstract "Although large numbers of diseases are primary to the oral cavity, periodontal diseases, by far, comprise those most frequently encountered. Periodontal diseases are infections, but host factors are important determinants of susceptibility and disease progression. Some forms of periodontitis, especially those seen in children and young adults, are related to abnormalities in host defense systems or to systemic diseases. The presence of periodontitis, especially in young individuals, conveys important information about general health. Periodontitis is recognized clinically by inflammation of the gingiva, bleeding, the presence of periodontal pockets, exudation, and tooth mobility. These diseases generally are painless until near their terminal stages. Periodontitis affects approximately 75% of adults under age 65, and almost all older individuals. Approximately 10% of adult Americans have severe periodontitis. Prevalence in children is lower. Several different kinds of periodontitis exist, and these differ in their etiology, natural history, and response to therapy. Prepubertal periodontitis affects the primary teeth of young children. The generalized form, observed in all children with LAD syndrome, rapidly results in loss of the teeth. The localized form, which is far less severe, is indicative of defective PMN chemotaxis. Juvenile periodontitis is observed in teenagers and begins at the circumpubertal period. Affected individuals manifest an abnormality in a surface glycoprotein designated GP110 and an abnormally low number of cell surface receptors for chemoattractants on the phagocytic cells. Abnormal PMN cell and monocyte motility also are observed in patients with rapidly progressive periodontitis. At this time, adult periodontitis, the most frequently observed type, has not been associated with abnormalities in host defense systems. Immunologic studies have been focused on patients with juvenile periodontitis and rapidly progressive periodontitis. Some of these patients mount a humoral immune response, whereas, for reasons that remain unknown, others do not. The IgG antibodies produced during infection are of relatively low avidity and predominated are by IgG2, a subclass considered to be relatively ineffective in opsonizing and enhancing phagocytosis and killing of bacteria by PMN cells. Following periodontal therapy, antibodies that are more highly avid and more effective in enhancing phagocytosis and killing are produced. The innate capacity of an individual to mount a robust humoral immune response may be a major determinant of susceptibility to periodontal diseases." @default.
• W2527303319 created "2016-10-07" @default.
• W2527303319 creator A5030426626 @default.
• W2527303319 creator A5033928415 @default.
• W2527303319 creator A5034115504 @default.
• W2527303319 creator A5043301541 @default.
• W2527303319 date "1993-05-01" @default.
• W2527303319 modified "2023-09-26" @default.
• W2527303319 title "CLINICAL AND IMMUNOLOGIC ASPECTS OF PERIODONTITIS" @default.
• W2527303319 cites W1506896023 @default.
• W2527303319 cites W1811854547 @default.
• W2527303319 cites W1963583786 @default.
• W2527303319 cites W1965974354 @default.
• W2527303319 cites W1966165870 @default.
• W2527303319 cites W1979076362 @default.
• W2527303319 cites W1980752371 @default.
• W2527303319 cites W1997386790 @default.
• W2527303319 cites W2011020802 @default.
• W2527303319 cites W2016732963 @default.
• W2527303319 cites W2028094185 @default.
• W2527303319 cites W2032664626 @default.
• W2527303319 cites W2048492356 @default.
• W2527303319 cites W2054437684 @default.
• W2527303319 cites W2064106265 @default.
• W2527303319 cites W2079878663 @default.
• W2527303319 cites W2088341649 @default.
• W2527303319 cites W2095932979 @default.
• W2527303319 cites W2098033313 @default.
• W2527303319 cites W2101176045 @default.
• W2527303319 cites W2108078808 @default.
• W2527303319 cites W2114953849 @default.
• W2527303319 cites W2120630606 @default.
• W2527303319 cites W2130430665 @default.
• W2527303319 cites W2141203380 @default.
• W2527303319 cites W2147633732 @default.
• W2527303319 cites W2148401329 @default.
• W2527303319 cites W2150683262 @default.
• W2527303319 cites W2170836464 @default.
• W2527303319 cites W2178098775 @default.
• W2527303319 doi "https://doi.org/10.1016/s0889-8561(22)00171-0" @default.
• W2527303319 hasPublicationYear "1993" @default.
• W2527303319 type Work @default.
• W2527303319 sameAs 2527303319 @default.
• W2527303319 citedByCount "0" @default.
• W2527303319 crossrefType "journal-article" @default.
• W2527303319 hasAuthorship W2527303319A5030426626 @default.
• W2527303319 hasAuthorship W2527303319A5033928415 @default.
• W2527303319 hasAuthorship W2527303319A5034115504 @default.
• W2527303319 hasAuthorship W2527303319A5043301541 @default.
• W2527303319 hasConcept C137627325 @default.
• W2527303319 hasConcept C142724271 @default.
• W2527303319 hasConcept C199343813 @default.
• W2527303319 hasConcept C203014093 @default.
• W2527303319 hasConcept C2776914184 @default.
• W2527303319 hasConcept C2778883934 @default.
• W2527303319 hasConcept C2780385504 @default.
• W2527303319 hasConcept C2780791200 @default.
• W2527303319 hasConcept C71924100 @default.
• W2527303319 hasConceptScore W2527303319C137627325 @default.
• W2527303319 hasConceptScore W2527303319C142724271 @default.
• W2527303319 hasConceptScore W2527303319C199343813 @default.
• W2527303319 hasConceptScore W2527303319C203014093 @default.
• W2527303319 hasConceptScore W2527303319C2776914184 @default.
• W2527303319 hasConceptScore W2527303319C2778883934 @default.
• W2527303319 hasConceptScore W2527303319C2780385504 @default.
• W2527303319 hasConceptScore W2527303319C2780791200 @default.
• W2527303319 hasConceptScore W2527303319C71924100 @default.
• W2527303319 hasIssue "2" @default.
• W2527303319 hasLocation W25273033191 @default.
• W2527303319 hasOpenAccess W2527303319 @default.
• W2527303319 hasPrimaryLocation W25273033191 @default.
• W2527303319 hasRelatedWork W1999860786 @default.
• W2527303319 hasRelatedWork W2060530145 @default.
• W2527303319 hasRelatedWork W2078096258 @default.
• W2527303319 hasRelatedWork W2125583390 @default.
• W2527303319 hasRelatedWork W2329431380 @default.
• W2527303319 hasRelatedWork W2738981461 @default.
• W2527303319 hasRelatedWork W2896857921 @default.
• W2527303319 hasRelatedWork W2982146709 @default.
• W2527303319 hasRelatedWork W3177687610 @default.
• W2527303319 hasRelatedWork W4214493149 @default.
• W2527303319 hasVolume "13" @default.
• W2527303319 isParatext "false" @default.
• W2527303319 isRetracted "false" @default.
• W2527303319 magId "2527303319" @default.
• W2527303319 workType "article" @default.