Matches in SemOpenAlex for { <https://semopenalex.org/work/W2527553837> ?p ?o ?g. }
- W2527553837 endingPage "123" @default.
- W2527553837 startingPage "117" @default.
- W2527553837 abstract "Natural enzymes that catalyze Diels-Alder reactions have long been sought after, yet few enzymes have been experimentally confirmed to perform this reaction. In the past five years, several stand-alone enzymes that can catalyze the Diels-Alder reaction had been identified and characterized. Among which, the crystal structures of SpnF, PyrI4 and AbyU have been determined. The structures of PyrI4 and AbyU, which are involved in spirotetronate/spirotetramate biosynthesis, are particularly informative since they shed light on how a natural catalyst captures the flexible substrate and facilitates the intramolecular Diels-Alder reaction through stabilization of the transition state in catalysis. These pioneering studies will inspire the design of artificial catalysts for Diels-Alder reactions." @default.
- W2527553837 created "2016-10-07" @default.
- W2527553837 creator A5008654485 @default.
- W2527553837 creator A5029481202 @default.
- W2527553837 date "2016-12-01" @default.
- W2527553837 modified "2023-10-16" @default.
- W2527553837 title "Mechanistic insights into Diels-Alder reactions in natural product biosynthesis" @default.
- W2527553837 cites W1612553237 @default.
- W2527553837 cites W1848034425 @default.
- W2527553837 cites W1869941822 @default.
- W2527553837 cites W1967873308 @default.
- W2527553837 cites W1967916082 @default.
- W2527553837 cites W1980769545 @default.
- W2527553837 cites W1983829868 @default.
- W2527553837 cites W1985672936 @default.
- W2527553837 cites W1988948560 @default.
- W2527553837 cites W2000547662 @default.
- W2527553837 cites W2001088365 @default.
- W2527553837 cites W2006193478 @default.
- W2527553837 cites W2008659388 @default.
- W2527553837 cites W2010111858 @default.
- W2527553837 cites W2012457974 @default.
- W2527553837 cites W2012643496 @default.
- W2527553837 cites W2014045288 @default.
- W2527553837 cites W2014095551 @default.
- W2527553837 cites W2034011943 @default.
- W2527553837 cites W2041324196 @default.
- W2527553837 cites W2053700413 @default.
- W2527553837 cites W2063178052 @default.
- W2527553837 cites W2065304507 @default.
- W2527553837 cites W2066381187 @default.
- W2527553837 cites W2073687063 @default.
- W2527553837 cites W2076972711 @default.
- W2527553837 cites W2083663804 @default.
- W2527553837 cites W2085884253 @default.
- W2527553837 cites W2086416477 @default.
- W2527553837 cites W2086424264 @default.
- W2527553837 cites W2089277461 @default.
- W2527553837 cites W2093386502 @default.
- W2527553837 cites W2095080395 @default.
- W2527553837 cites W2125550108 @default.
- W2527553837 cites W2131840797 @default.
- W2527553837 cites W2153445710 @default.
- W2527553837 cites W2155846338 @default.
- W2527553837 cites W2161747039 @default.
- W2527553837 cites W2209833992 @default.
- W2527553837 cites W2222894040 @default.
- W2527553837 cites W2231071237 @default.
- W2527553837 cites W2266627069 @default.
- W2527553837 cites W2275656862 @default.
- W2527553837 cites W2280489664 @default.
- W2527553837 cites W2337695086 @default.
- W2527553837 cites W2342370956 @default.
- W2527553837 cites W2346461087 @default.
- W2527553837 cites W2406101902 @default.
- W2527553837 cites W2429821632 @default.
- W2527553837 cites W2950545025 @default.
- W2527553837 doi "https://doi.org/10.1016/j.cbpa.2016.09.015" @default.
- W2527553837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27697700" @default.
- W2527553837 hasPublicationYear "2016" @default.
- W2527553837 type Work @default.
- W2527553837 sameAs 2527553837 @default.
- W2527553837 citedByCount "30" @default.
- W2527553837 countsByYear W25275538372016 @default.
- W2527553837 countsByYear W25275538372017 @default.
- W2527553837 countsByYear W25275538372018 @default.
- W2527553837 countsByYear W25275538372019 @default.
- W2527553837 countsByYear W25275538372021 @default.
- W2527553837 countsByYear W25275538372022 @default.
- W2527553837 countsByYear W25275538372023 @default.
- W2527553837 crossrefType "journal-article" @default.
- W2527553837 hasAuthorship W2527553837A5008654485 @default.
- W2527553837 hasAuthorship W2527553837A5029481202 @default.
- W2527553837 hasBestOaLocation W25275538371 @default.
- W2527553837 hasConcept C161790260 @default.
- W2527553837 hasConcept C178790620 @default.
- W2527553837 hasConcept C181199279 @default.
- W2527553837 hasConcept C185592680 @default.
- W2527553837 hasConcept C18903297 @default.
- W2527553837 hasConcept C2777289219 @default.
- W2527553837 hasConcept C2779396153 @default.
- W2527553837 hasConcept C2779940776 @default.
- W2527553837 hasConcept C553450214 @default.
- W2527553837 hasConcept C69118441 @default.
- W2527553837 hasConcept C71240020 @default.
- W2527553837 hasConcept C75079739 @default.
- W2527553837 hasConcept C86803240 @default.
- W2527553837 hasConceptScore W2527553837C161790260 @default.
- W2527553837 hasConceptScore W2527553837C178790620 @default.
- W2527553837 hasConceptScore W2527553837C181199279 @default.
- W2527553837 hasConceptScore W2527553837C185592680 @default.
- W2527553837 hasConceptScore W2527553837C18903297 @default.
- W2527553837 hasConceptScore W2527553837C2777289219 @default.
- W2527553837 hasConceptScore W2527553837C2779396153 @default.
- W2527553837 hasConceptScore W2527553837C2779940776 @default.
- W2527553837 hasConceptScore W2527553837C553450214 @default.
- W2527553837 hasConceptScore W2527553837C69118441 @default.
- W2527553837 hasConceptScore W2527553837C71240020 @default.