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• W2527590340 abstract "<p class=abstract><strong>Background:</strong> <span lang=EN-GB>Type 2 diabetic women are at higher risk of developing atherogenic dyslipidemia. The major possible risk factors are obesity, abdominal fat accumulation and poor glycaemic control. However, menopause-related changes could be another determinant. The aim of this study was to evaluate the interrelationships of these risk factors and their independent effects on atherogenic indices in type 2 diabetes women</span>.</p><p class=abstract><strong>Methods:</strong> <span lang=EN-GB>A prospective, cross-sectional study, which includes 160 women agreed to participate in this study. Anthropometrics, biochemical parameters and blood pressure were measured. Atherogenic indices - total cholesterol-to-high-density lipoprotein cholesterol ratio (TC/HDL) and apolipoprotein (apo) B-to-apo A1 ratio, were calculated. Individual risk factors were examined in relationship to these atherogenic indices using correlation tests and logistic regression</span><span lang=EN-IN>. </span><span lang=EN-IN> </span></p><p class=abstract><strong>Results:</strong> <span lang=EN-GB>23.12% of the participants were normal weight and 76.87% were overweight/obese. The overall mean age was 57.70±11.16 years. Diabetes duration (˃5years), anthropometric parameters, poor glycaemic control, high apo B and high level of low-density lipoprotein (LDL) were found to be significant determinants of atherogenic indices changes. </span><span lang=EN-GB>The TC/HDL ratio was weakly associated with both BMI and waist circumference. However, the apo B/apo A1 ratio provided positive correlations with anthropometric parameters, especially with waist circumference (<em>p</em>=0.185, r=0.108, r²=0.012), and this, in both pre and post-menopausal type 2 diabetic women</span>.</p><p class=abstract><strong>Conclusions:</strong> <span lang=EN-GB>The atherogenic risk, estimated by TC/HDL and apo B/apo A1 ratios, becomes more severe with higher anthropometric parameters (BMI and waist circumference), diabetes duration and poor glycaemic control in type 2 diabetes women and this during both premenopausal and postmenopausal periods</span><span lang=EN-IN>. </span></p>" @default.
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• W2527590340 date "2016-09-26" @default.
• W2527590340 modified "2023-10-18" @default.
• W2527590340 title "Factors influencing atherogenic indices in type 2 diabetic women in northwestern Algeria" @default.
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• W2527590340 doi "https://doi.org/10.18203/issn.2454-2156.intjscirep20163397" @default.
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