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- W2527902016 abstract "Epidemiological data reflect the prevalence of renal damage in chronic heart failure (CHF) varies from 25 to 60%. Reduced glomerular filtration rate is considered as a predictor of poor prognosis in heart failure with reduced ejection fraction of the left ventricle the risk of death increases by 3,8 times, with preserved ejection fraction — 2,9 times. The aim of the study was to investigate the clinical characteristics of patients with CHF and chronic kidney disease (CKD) compared with patients without comorbidity. Material and methods. We examined 188 patients (91 men and 97 women) with CHF and CKD and chronic HF patients without comorbid pathology, an average age of 66,8±10,1 years. Glomerular filtration rate was calculated by MDRD and CKD-EPI. Chronic kidney disease was verified in accordance with national guidelines «cardiovascular risk and chronic kidney disease: strategies for cardio-nephroprotective», 2013. Results and their discussion. Glomerular filtration rate in patients with CHF and CKD amounted to (51,5±19,1) ml/ min/1,73 m 2 , in the comparison group — (71,1±11,7) ml/min/1,73 m 2 . Showed significantly more pronounced differences in daily excretion of protein in the two groups. Patients with CKD were older age, dominated by women; among them, the majority of patients in history had diabetes mellitus. Conclusion. The kidney function occurs in one third of patients with chronic heart failure (cardiorenal syndrome of the 2nd type). The results of the study confirm that the presence of proteinuria and reduced GFR reflect severity in cardiovascular and renal systems." @default.
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- W2527902016 date "2015-01-01" @default.
- W2527902016 modified "2023-09-27" @default.
- W2527902016 title "the clinical characteristics of patients with heart failure in combination with chronic kidney diseas" @default.
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